Antigen Information

General Information of This Antigen (ID: TAR0GLSWQ)
Antigen Name
CD276 antigen (CD276)
Gene Name
CD276
Gene ID
80381
Synonym
B7H3; PSEC0249; UNQ309; PRO352; 4Ig-B7-H3;B7 homolog 3;Costimulatory molecule;CD276
Sequence
MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL
AQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSF
TCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQD
GQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQ
RSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEG
RDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPY
SKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLF
DVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIAL
LVALAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDSKEDDGQEIA

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Family
HIV-1 env protein family
Function
May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

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Uniprot Entry
CD276_HUMAN
HGNC ID
HGNC:19137
KEGG ID
hsa:80381
Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens
ADC Name Payload Target Linker ADC Info
1D1-01-ADC-Tb1-1 [1]
1D1-01-ADC-Tb1-1 payload
Undisclosed
1D1-01-ADC-Tb1-1 linker
 ADC Info 
1D1-01-ADC-Tb1-2 [1]
1D1-01-ADC-Tb1-2 payload
Undisclosed
1D1-01-ADC-Tb1-2 linker
 ADC Info 
1D1-01-ADC-Tb1-3 [1]
1D1-01-ADC-Tb1-3 payload
Undisclosed
1D1-01-ADC-Tb1-3 linker
 ADC Info 
1D1-01-ADC-Tb1-4 [1]
1D1-01-ADC-Tb1-4 payload
Undisclosed
1D1-01-ADC-Tb1-4 linker
 ADC Info 
1D1-01-ADC-Tb1-5 [1]
1D1-01-ADC-Tb1-5 payload
Undisclosed
1D1-01-ADC-Tb1-5 linker
 ADC Info 
1D1-01-ADC-Tb1-6 [1]
1D1-01-ADC-Tb1-6 payload
Undisclosed
1D1-01-ADC-Tb1-6 linker
 ADC Info 
1D1-01-ADC-Tb1-7 [1]
1D1-01-ADC-Tb1-7 payload
Undisclosed
1D1-01-ADC-Tb1-7 linker
 ADC Info 
1D1-01-ADC-Tb1-8 [1]
1D1-01-ADC-Tb1-8 payload
Undisclosed
1D1-01-ADC-Tb1-8 linker
 ADC Info 
1D1-01-ADC-Tb1-9 [1]
1D1-01-ADC-Tb1-9 payload
Undisclosed
1D1-01-ADC-Tb1-9 linker
 ADC Info 
1D1-01-ADC-Tb1-10 [1]
1D1-01-ADC-Tb1-10 payload
Undisclosed
1D1-01-ADC-Tb1-10 linker
 ADC Info 
1D1-01-ADC-Tb1-11 [1]
1D1-01-ADC-Tb1-11 payload
Undisclosed
1D1-01-ADC-Tb1-11 linker
 ADC Info 
1D1-01-ADC-Tb1-12 [1]
1D1-01-ADC-Tb1-12 payload
Undisclosed
1D1-01-ADC-Tb1-12 linker
 ADC Info 
1D1-01-ADC-Tb1-13 [1]
1D1-01-ADC-Tb1-13 payload
Undisclosed
1D1-01-ADC-Tb1-13 linker
 ADC Info 
1D1-01-ADC-Tb1-14 [1]
1D1-01-ADC-Tb1-14 payload
Undisclosed
1D1-01-ADC-Tb1-14 linker
 ADC Info 
1D1-01-ADC-Tb1-15 [1]
1D1-01-ADC-Tb1-15 payload
Undisclosed
1D1-01-ADC-Tb1-15 linker
 ADC Info 
1D1-01-ADC-Tb1-16 [1]
1D1-01-ADC-Tb1-16 payload
Undisclosed
1D1-01-ADC-Tb1-16 linker
 ADC Info 
1D1-01-ADC-Tb1-17 [1]
1D1-01-ADC-Tb1-17 payload
Undisclosed
1D1-01-ADC-Tb1-17 linker
 ADC Info 
1D1-01-ADC-Tb1-18 [1]
1D1-01-ADC-Tb1-18 payload
Undisclosed
1D1-01-ADC-Tb1-18 linker
 ADC Info 
1D1-01-ADC-Tb1-19 [1]
1D1-01-ADC-Tb1-19 payload
Undisclosed
1D1-01-ADC-Tb1-19 linker
 ADC Info 
1D1-01-ADC-Tb1-20 [1]
1D1-01-ADC-Tb1-20 payload
Undisclosed
1D1-01-ADC-Tb1-20 linker
 ADC Info 
1D1-01-ADC-Tb1-21 [1]
1D1-01-ADC-Tb1-21 payload
Undisclosed
1D1-01-ADC-Tb1-21 linker
 ADC Info 
1D1-01-ADC-Tb1-22 [1]
1D1-01-ADC-Tb1-22 payload
Undisclosed
1D1-01-ADC-Tb1-22 linker
 ADC Info 
1D1-01-ADC-Tb1-23 [1]
1D1-01-ADC-Tb1-23 payload
Undisclosed
1D1-01-ADC-Tb1-23 linker
 ADC Info 
1D1-01-ADC-Tb1-24 [1]
1D1-01-ADC-Tb1-24 payload
Undisclosed
1D1-01-ADC-Tb1-24 linker
 ADC Info 
1D1-01-ADC-Tb1-25 [1]
1D1-01-ADC-Tb1-25 payload
Undisclosed
1D1-01-ADC-Tb1-25 linker
 ADC Info 
1D1-01-ADC-Tb1-26 [1]
1D1-01-ADC-Tb1-26 payload
Undisclosed
1D1-01-ADC-Tb1-26 linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
WO2020063676A1 ADC-25 [2]
WO2020063676A1_ADC-25 payload
Undisclosed
WO2020063676A1_ADC-25 linker
 ADC Info 
WO2020063676A1 ADC-26 [2]
WO2020063676A1_ADC-26 payload
Undisclosed
WO2020063676A1_ADC-26 linker
 ADC Info 
WO2020063676A1 ADC-27 [2]
WO2020063676A1_ADC-27 payload
Undisclosed
WO2020063676A1_ADC-27 linker
 ADC Info 
WO2020063676A1 ADC-28 [2]
WO2020063676A1_ADC-28 payload
Undisclosed
WO2020063676A1_ADC-28 linker
 ADC Info 
WO2020063676A1 ADC-29 [2]
WO2020063676A1_ADC-29 payload
Undisclosed
WO2020063676A1_ADC-29 linker
 ADC Info 
WO2020063676A1 ADC-30 [2]
WO2020063676A1_ADC-30 payload
Undisclosed
WO2020063676A1_ADC-30 linker
 ADC Info 
WO2020063676A1 ADC-31 [2]
WO2020063676A1_ADC-31 payload
Undisclosed
WO2020063676A1_ADC-31 linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
40285886 7300-LP1003 [3]
Camptothecin derivative 095
Undisclosed
a polyethylene glycol-modified straight-link agent
 ADC Info 
40285886 7300-LP2004 [3]
Camptothecin derivative 095
Undisclosed
a polyethylene glycol-modified branched-link agent
 ADC Info 
40285886 7300-LP3004 [3]
Camptothecin derivative 095
Undisclosed
a PSar-modified branched-link agent
 ADC Info 
40285886 7300-Deruxtecan [3]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
Mc-Gly-Gly-Phe-Gly
 ADC Info 
Anti-B7-H3 mAb
 Antibody Info 
ADC Name Payload Target Linker ADC Info
BB-1712 [4]
Eribulin
Microtubule (MT)
A cleavable linker
 ADC Info 
Anti-b7h3
 Antibody Info 
ADC Name Payload Target Linker ADC Info
WBP301088-X2 [5]
Topo1 inhibitor F
DNA topoisomerase I (TOP1)
Mc-Gly-Gly-Phe-Gly
 ADC Info 
Anti-B7H3 antibody
 Antibody Info 
ADC Name Payload Target Linker ADC Info
Vobramitamab tavatecan
Exatecan
DNA topoisomerase 1 (TOP1)
Synaffix linker
 ADC Info 
MHB088C
MH30010008
DNA topoisomerase 1 (TOP1)
A cleavable linker
 ADC Info 
ILB-3101
Eribulin
Microtubule (MT)
A cleavable linker
 ADC Info 
DB-1311
P1021
DNA topoisomerase 1 (TOP1)
Mc-Gly-Gly-Phe-Gly
 ADC Info 
BAT8009
Exatecan
DNA topoisomerase 1 (TOP1)
A cleavable linker
 ADC Info 
7MW3711 [6]
Mtoxin
DNA topoisomerase 1 (TOP1)
A cleavable linker
 ADC Info 
BGB-C354 [7]
TOP1 inhibitor
DNA topoisomerase 1 (TOP1)
A cleavable linker
 ADC Info 
ICP-B794
TOP1 inhibitor
DNA topoisomerase 1 (TOP1)
A cleavable linker
 ADC Info 
SYS6043
JS-1
DNA topoisomerase 1 (TOP1)
Mc-Gly-Gly-Phe-Gly
 ADC Info 
SKB500
KL610348
DNA topoisomerase 1 (TOP1)
A cleavable linker
 ADC Info 
ITC-6146RO
Duocarmycin derivative
Human deoxyribonucleic acid (hDNA)
Self-immolative OHPAS linker
 ADC Info 
Anti-B7H3 mAb 2E3-02
 Antibody Info 
ADC Name Payload Target Linker ADC Info
B7H3-ADC-01 [1]
B7H3-ADC-01 payload
Undisclosed
B7H3-ADC-01 linker
 ADC Info 
B7H3-ADC-02 [1]
B7H3-ADC-02 payload
Undisclosed
B7H3-ADC-02 linker
 ADC Info 
B7H3-ADC-03 [1]
B7H3-ADC-03 payload
Undisclosed
B7H3-ADC-03 linker
 ADC Info 
B7H3-ADC-04 (DAR8) [1]
B7H3-ADC-04 payload
Undisclosed
B7H3-ADC-04 linker
 ADC Info 
B7H3-ADC-05 (DAR8) [1]
B7H3-ADC-05(DAR8) payload
Undisclosed
B7H3-ADC-05(DAR8) linker
 ADC Info 
B7H3-ADC-05 (DAR4) [1]
B7H3-ADC-05(DAR8) payload
Undisclosed
B7H3-ADC-05(DAR4) linker
 ADC Info 
B7H3-ADC-06 (DAR8) [1]
B7H3-ADC-06 payload
Undisclosed
B7H3-ADC-06 linker
 ADC Info 
B7H3-ADC-07 (DAR8) [1]
B7H3-ADC-07(DAR8) payload
Undisclosed
B7H3-ADC-07(DAR8) linker
 ADC Info 
B7H3-ADC-07 (DAR2) [1]
B7H3-ADC-07(DAR2) payload
Undisclosed
B7H3-ADC-07(DAR2) linker
 ADC Info 
B7H3-ADC-07 (DAR4) [1]
B7H3-ADC-07(DAR4) payload
Undisclosed
B7H3-ADC-07(DAR4) linker
 ADC Info 
B7H3-ADC-07 (DAR6) [1]
B7H3-ADC-07(DAR6) payload
Undisclosed
B7H3-ADC-07(DAR6) linker
 ADC Info 
B7H3-ADC-08 (DAR8) [1]
B7H3-ADC-08(DAR8) payload
Undisclosed
B7H3-ADC-08(DAR8) linker
 ADC Info 
B7H3-ADC-08 (DAR4) [1]
B7H3-ADC-08(DAR4) payload
Undisclosed
B7H3-ADC-08(DAR4) linker
 ADC Info 
B7H3-ADC-09 (DAR8) [1]
B7H3-ADC-09 payload
Undisclosed
B7H3-ADC-09 linker
 ADC Info 
B7H3-ADC-10 (DAR8) [1]
B7H3-ADC-10 payload
Undisclosed
B7H3-ADC-10 linker
 ADC Info 
B7H3-ADC-11 (DAR8) [1]
B7H3-ADC-11 payload
Undisclosed
B7H3-ADC-11 linker
 ADC Info 
B7H3-ADC-12 (DAR8) [1]
B7H3-ADC-12 payload
Undisclosed
B7H3-ADC-12 linker
 ADC Info 
B7H3-ADC-13 (DAR8) [1]
B7H3-ADC-13 payload
Undisclosed
B7H3-ADC-13 linker
 ADC Info 
B7H3-ADC-14 (DAR8) [1]
B7H3-ADC-14 payload
Undisclosed
B7H3-ADC-14 linker
 ADC Info 
B7H3-ADC-15 (DAR8) [1]
B7H3-ADC-15(DAR8) payload
Undisclosed
B7H3-ADC-15(DAR8) linker
 ADC Info 
B7H3-ADC-15 (DAR4) [1]
B7H3-ADC-15(DAR4) payload
Undisclosed
B7H3-ADC-15(DAR4) linker
 ADC Info 
B7H3-ADC-16 (DAR8) [1]
B7H3-ADC-16 payload
Undisclosed
B7H3-ADC-16 linker
 ADC Info 
B7H3-ADC-17 [1]
B7H3-ADC-17 payload
Undisclosed
B7H3-ADC-17 linker
 ADC Info 
B7H3-ADC-18 (DAR8) [1]
B7H3-ADC-18 payload
Undisclosed
B7H3-ADC-18 linker
 ADC Info 
B7H3-ADC-19 (DAR8) [1]
B7H3-ADC-19 payload
Undisclosed
B7H3-ADC-19 linker
 ADC Info 
B7H3-ADC-20 (DAR8) [1]
B7H3-ADC-20 payload
Undisclosed
B7H3-ADC-20 linker
 ADC Info 
B7H3-ADC-22 (DAR8) [1]
B7H3-ADC-22 payload
Undisclosed
B7H3-ADC-22 linker
 ADC Info 
B7H3-ADC-23 (DAR8) [1]
B7H3-ADC-23 payload
Undisclosed
B7H3-ADC-23 linker
 ADC Info 
B7H3-ADC-24 (DAR8) [1]
B7H3-ADC-24 payload
Undisclosed
B7H3-ADC-24 linker
 ADC Info 
B7H3-ADC-25 (DAR8) [1]
B7H3-ADC-25 payload
Undisclosed
B7H3-ADC-25 linker
 ADC Info 
B7H3-ADC-27 (DAR8) [1]
B7H3-ADC-27 payload
Undisclosed
B7H3-ADC-27 linker
 ADC Info 
B7H3-ADC-28 (DAR8) [1]
B7H3-ADC-28 payload
Undisclosed
B7H3-ADC-28 linker
 ADC Info 
B7H3-ADC-32 (DAR8) [1]
B7H3-ADC-32 payload
Undisclosed
B7H3-ADC-32 linker
 ADC Info 
B7H3-ADC-33 (DAR8) [1]
B7H3-ADC-33(DAR8) payload
Undisclosed
B7H3-ADC-33(DAR8) linker
 ADC Info 
B7H3-ADC-33 (DAR4) [1]
B7H3-ADC-33(DAR4) payload
Undisclosed
B7H3-ADC-33(DAR4) linker
 ADC Info 
B7H3-ADC-001 [8]
DL014-payload; DL003-payload
Undisclosed
DL014-Linker; DL003-Linker
 ADC Info 
B7H3-ADC-002 [8]
DL014-payload; DL003-payload
Undisclosed
DL014-Linker; DL003-Linker
 ADC Info 
B7H3-ADC-003 [8]
DL014-payload; DL003-payload
Undisclosed
DL014-Linker; DL003-Linker
 ADC Info 
Anti-CD276 mAb
 Antibody Info 
ADC Name Payload Target Linker ADC Info
Anti-CD276 mAb-MMAF [9]
Monomethyl auristatin F
Microtubule (MT)
Undisclosed
 ADC Info 
Anti-CD276 mAb h1702DS
 Antibody Info 
ADC Name Payload Target Linker ADC Info
WO2020063673A1 ADC-1 [10]
WO2020063673A1_ADC-1 payload
Undisclosed
WO2020063673A1_ADC-1 linker
 ADC Info 
WO2020063673A1 ADC-2 [10]
WO2020063673A1_ADC-2 payload
Undisclosed
WO2020063673A1_ADC-2 linker
 ADC Info 
WO2020063673A1 ADC-3 [10]
WO2020063673A1_ADC-3 payload
Undisclosed
WO2020063673A1_ADC-3 linker
 ADC Info 
WO2020063673A1 ADC-4 [10]
WO2020063673A1_ADC-4 payload
Undisclosed
WO2020063673A1_ADC-4 linker
 ADC Info 
WO2020063673A1 ADC-5 [10]
WO2020063673A1_ADC-5 payload
Undisclosed
WO2020063673A1_ADC-5 linker
 ADC Info 
WO2020063673A1 ADC-6 [10]
WO2020063673A1_ADC-6 payload
Undisclosed
WO2020063673A1_ADC-6 linker
 ADC Info 
WO2020063673A1 ADC-7 [10]
WO2020063673A1_ADC-7 payload
Undisclosed
WO2020063673A1_ADC-7 linker
 ADC Info 
WO2020063673A1 ADC-8 [10]
WO2020063673A1_ADC-8 payload
Undisclosed
WO2020063673A1_ADC-8 linker
 ADC Info 
Anti-CD276 mAb m276-SL
 Antibody Info 
ADC Name Payload Target Linker ADC Info
M276-SL-PBD [11]
PBD dimer
Human Deoxyribonucleic acid (hDNA)
Mc-Val-Ala
 ADC Info 
Anti-human CD276 mAb
 Antibody Info 
ADC Name Payload Target Linker ADC Info
B7H3-EC3 DAR4.1 [12]
NAMPT inhibitor 4
Nicotinamide phosphoribosyltransferase (NAMPT)
Mc-Val-Ala
 ADC Info 
B7H3-EC3 DAR7.8 [12]
NAMPT inhibitor 4
Nicotinamide phosphoribosyltransferase (NAMPT)
Mc-Val-Ala
 ADC Info 
B7H3-EC5 [12]
NAMPT inhibitor 6
Nicotinamide phosphoribosyltransferase (NAMPT)
Open-chain glycine maleimide-PEG
 ADC Info 
B7H3-EC4 [12]
NAMPT inhibitor 5
Nicotinamide phosphoribosyltransferase (NAMPT)
Open-chain glycine maleimide
 ADC Info 
B7H3-EC2 [12]
NAMPT inhibitor 6
Nicotinamide phosphoribosyltransferase (NAMPT)
Maleimido-caproyl
 ADC Info 
B7H3-EC1 [12]
NAMPT inhibitor 4
Nicotinamide phosphoribosyltransferase (NAMPT)
Maleimido-caproyl
 ADC Info 
CN109069633A ADC-1 [13]
CN109069633A ADC-1 payload
Undisclosed
CN109069633A ADC-1 linker
 ADC Info 
CN109069633A ADC-2 [13]
CN109069633A ADC-2 payload
Undisclosed
CN109069633A ADC-2 linker
 ADC Info 
CN109069633A ADC-3 [13]
CN109069633A ADC-3 payload
Undisclosed
CN109069633A ADC-3 linker
 ADC Info 
Antibody V3
 Antibody Info 
ADC Name Payload Target Linker ADC Info
CN115969996A ADC1 [14]
Exatecan
DNA topoisomerase 1 (TOP1)
CB07 linker
 ADC Info 
CN115969996A ADC2 [14]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
Mc-Gly-Gly-Phe-Gly
 ADC Info 
CN115969996A ADC3 [14]
Exatecan
DNA topoisomerase 1 (TOP1)
CB07 linker
 ADC Info 
B7-H3 mAb 401
 Antibody Info 
ADC Name Payload Target Linker ADC Info
37235999 ADC 401-4 [15]
Monomethyl auristatin E
Microtubule (MT)
Fmoc-Val-Cit-PAB-PNP
 ADC Info 
B7-H3-ABBV-155
 Antibody Info 
ADC Name Payload Target Linker ADC Info
B7-H3-ABBV-155-L101-D101 [16]
Compound D101
Undisclosed
L101 linker
 ADC Info 
B7-H3-ABBV-155-L102-D101 [16]
Compound D101
Undisclosed
L102 linker
 ADC Info 
B7-H3-ABBV-155-L103-D101 [16]
Compound D101
Undisclosed
L103 linker
 ADC Info 
B7-H3-ABBV-155-L101-D102 [16]
Compound D102
Undisclosed
L101 linker
 ADC Info 
B7-H3-ABBV-155-L101-D103 [16]
Compound D103
Undisclosed
L101 linker
 ADC Info 
B7-H3-ABBV-155-L101-D104 [16]
Compound D104
Undisclosed
L101 linker
 ADC Info 
B7-H3-ABBV-155-L102-D102 [16]
Compound D102
Undisclosed
L102 linker
 ADC Info 
B7-H3-ABBV-155-L102-D103 [16]
Compound D103
Undisclosed
L102 linker
 ADC Info 
B7-H3-ABBV-155-L102-D104 [16]
Compound D104
Undisclosed
L102 linker
 ADC Info 
B7-H3-DS-5573a
 Antibody Info 
ADC Name Payload Target Linker ADC Info
B7-H3-DS-5573a-L101-D101 [16]
Compound D101
Undisclosed
L101 linker
 ADC Info 
B7-H3-DS-5573a-L102-D101 [16]
Compound D101
Undisclosed
L102 linker
 ADC Info 
B7-H3-DS-5573a-L103-D101 [16]
Compound D101
Undisclosed
L103 linker
 ADC Info 
B7-H3-DS-5573a-L101-D102 [16]
Compound D102
Undisclosed
L101 linker
 ADC Info 
B7-H3-DS-5573a-L101-D103 [16]
Compound D103
Undisclosed
L101 linker
 ADC Info 
B7-H3-DS-5573a-L101-D104 [16]
Compound D104
Undisclosed
L101 linker
 ADC Info 
B7-H3-DS-5573a-L102-D102 [16]
Compound D102
Undisclosed
L102 linker
 ADC Info 
B7-H3-DS-5573a-L102-D103 [16]
Compound D103
Undisclosed
L102 linker
 ADC Info 
B7-H3-DS-5573a-L102-D104 [16]
Compound D104
Undisclosed
L102 linker
 ADC Info 
B7H3 antibody
 Antibody Info 
ADC Name Payload Target Linker ADC Info
CN115429893A ADC15 [17]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
B7H3 Y107 A121C
 Antibody Info 
ADC Name Payload Target Linker ADC Info
CN118414170A T-2-AB [18]
T-2
Undisclosed
T-2 linker
 ADC Info 
CN118414170A T-3-AB [18]
T-3
Undisclosed
T-3 linker
 ADC Info 
CN118414170A T-4-AB [18]
T-4
Undisclosed
T-4 linker
 ADC Info 
CN118414170A T-5-AB [18]
T-3
Undisclosed
T-5 linker
 ADC Info 
CN118414170A T-6-AB [18]
T-6
Undisclosed
T-6 linker
 ADC Info 
CN118414170A T-8-AB [18]
T-8
Undisclosed
T-8 linker
 ADC Info 
CN118414170A T-9-AB [18]
T-9
Undisclosed
T-9 linker
 ADC Info 
CN118414170A T-10-AB [18]
T-10
Undisclosed
T-5 linker
 ADC Info 
CN118414170A T-11-AB [18]
T-11
Undisclosed
T-5 linker
 ADC Info 
CN118414170A T-12-AB [18]
T-12
Undisclosed
T-5 linker
 ADC Info 
CN118414170A T-13-AB [18]
T-13
Undisclosed
T-5 linker
 ADC Info 
CN118414170A T-14-AB [18]
T-14
Undisclosed
T-14 linker
 ADC Info 
CN118414170A T-15-AB [18]
T-15
Undisclosed
T-4 linker
 ADC Info 
CN118414170A T-102-AB [18]
T-102
Undisclosed
T-102 linker
 ADC Info 
CN118414170A T-103-AB [18]
T-103
Undisclosed
T-102 linker
 ADC Info 
CN118414170A T-104-AB [18]
T-104
Undisclosed
T-102 linker
 ADC Info 
CN118414170A T-110-AB [18]
T-110
Undisclosed
T-102 linker
 ADC Info 
CN118414170A T-111-AB [18]
T-111
Undisclosed
T-102 linker
 ADC Info 
CN118414170A T-112-AB [18]
T-112
Undisclosed
T-102 linker
 ADC Info 
CN118414170A T-113-AB [18]
T-113
Undisclosed
T-102 linker
 ADC Info 
CN118414170A T-115-AB [18]
T-115
Undisclosed
T-102 linker
 ADC Info 
CN118414170A T-116-AB [18]
T-116
Undisclosed
T-102 linker
 ADC Info 
CN118414170A T-117-AB [18]
T-116
Undisclosed
T-117 linker
 ADC Info 
CN118414170A T-118-AB [18]
T-118
Undisclosed
T-102 linker
 ADC Info 
CN118414170A T-119-AB [18]
T-119
Undisclosed
T-102 linker
 ADC Info 
CN118414170A T-120-AB [18]
T-120
Undisclosed
T-102 linker
 ADC Info 
CN118414170A T-121-AB [18]
T-121
Undisclosed
T-102 linker
 ADC Info 
CN118414170A T-122-AB [18]
T-122
Undisclosed
T-102 linker
 ADC Info 
CN118414170A T-123-AB [18]
T-123
Undisclosed
T-102 linker
 ADC Info 
CN118414170A T-124-AB [18]
T-122
Undisclosed
T-124 linker
 ADC Info 
CN118414170A T-125-AB [18]
T-123
Undisclosed
T-125 linker
 ADC Info 
CN118414170A T-127-AB [18]
T-122
Undisclosed
Undisclosed
 ADC Info 
CN118414170A T-129-AB [18]
T-129
Undisclosed
Undisclosed
 ADC Info 
CN118414170A T-132-AB [18]
T-132
Undisclosed
T-132 linker
 ADC Info 
CN118414170A T-133-AB [18]
T-133
Undisclosed
T-132 linker
 ADC Info 
CN118414170A T-134-AB [18]
T-134
Undisclosed
T-132 linker
 ADC Info 
CN118414170A T-135-AB [18]
T-135
Undisclosed
T-132 linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
B7H3-C1-ADC-05 (DAR4) [1]
B7H3-C1-ADC-05(DAR4) payload
Undisclosed
B7H3-C1-ADC-05(DAR4) linker
 ADC Info 
B7H3-C1-ADC-07 (DAR4) [1]
B7H3-C1-ADC-07(DAR4) payload
Undisclosed
B7H3-C1-ADC-07(DAR4) linker
 ADC Info 
B7H3-C1-ADC-08 (DAR4) [1]
B7H3-C1-ADC-08(DAR4) payload
Undisclosed
B7H3-C1-ADC-08(DAR4) linker
 ADC Info 
B7H3-ADC-21 (DAR8) [1]
B7H3-ADC-21(DAR8) payload
Undisclosed
B7H3-ADC-21(DAR8) linker
 ADC Info 
B7H3-ADC-21 (DAR2) [1]
B7H3-ADC-21(DAR2) payload
Undisclosed
B7H3-ADC-21(DAR2) linker
 ADC Info 
B7H3-C1-ADC-21 (DAR4) [1]
B7H3-C1-ADC-21(DAR4) payload
Undisclosed
B7H3-C1-ADC-21(DAR4) linker
 ADC Info 
B7H3-ADC-21 (DAR6) [1]
B7H3-ADC-21(DAR6) payload
Undisclosed
B7H3-ADC-21(DAR6) linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
ChAb11-CZ [19]
chAb11-CZ payload
Undisclosed
chAb11-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
ChAb13-CZ [19]
chAb13-CZ payload
Undisclosed
chAb13-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
ChAb14-CZ [19]
chAb14-CZ payload
Undisclosed
chAb14-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
ChAb16-CZ [19]
chAb16-CZ payload
Undisclosed
chAb16-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
ChAb18-CZ [19]
chAb18-CZ payload
Undisclosed
chAb18-CZ linker
 ADC Info 
chAb2 (chimra IgG1)
 Antibody Info 
ADC Name Payload Target Linker ADC Info
ChAb2-CZ [19]
chAb2-CZ payload
Undisclosed
chAb2-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
ChAb3-CZ [19]
chAb3-CZ payload
Undisclosed
chAb3-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
ChAb4-CZ [19]
chAb4-CZ payload
Undisclosed
chAb4-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
ChAb6-CZ [19]
chAb6-CZ payload
Undisclosed
chAb6-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
ChmAb-A B7-H3-ADC [20]
Monomethyl auristatin E
Microtubule (MT)
Mc-Val-Cit-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
ChmAb-B B7-H3-ADC [20]
Monomethyl auristatin E
Microtubule (MT)
Mc-Val-Cit-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
ChmAb-C B7-H3-ADC [20]
Monomethyl auristatin E
Microtubule (MT)
Mc-Val-Cit-PABC
 ADC Info 
ADC Name Payload Target Linker ADC Info
ChmAb-D B7-H3-ADC [20]
Monomethyl auristatin E
Microtubule (MT)
Mc-Val-Cit-PABC
 ADC Info 
Enoblituzumab
 Antibody Info 
ADC Name Payload Target Linker ADC Info
Enoblituzumab-ADC-24-1 [2]
Enoblituzumab-ADC-24-1 payload
Undisclosed
Enoblituzumab-ADC-24-1 linker
 ADC Info 
Enoblituzumab-ADC-24-2 [2]
Enoblituzumab-ADC-24-2 payload
Undisclosed
Enoblituzumab-ADC-24-2 linker
 ADC Info 
Enoblituzumab-ADC-24-3 [2]
Enoblituzumab-ADC-24-3 payload
Undisclosed
Enoblituzumab-ADC-24-3 linker
 ADC Info 
Enoblituzumab-ADC-24-4 [2]
Enoblituzumab-ADC-24-4 payload
Undisclosed
Enoblituzumab-ADC-24-4 linker
 ADC Info 
Enoblituzumab-ADC-24-5 [2]
Enoblituzumab-ADC-24-5 payload
Undisclosed
Enoblituzumab-ADC-24-5 linker
 ADC Info 
Enoblituzumab-ADC-24-6 [2]
Enoblituzumab-ADC-24-6 payload
Undisclosed
Enoblituzumab-ADC-24-6 linker
 ADC Info 
Enoblituzumab-ADC-24-7 [2]
Enoblituzumab-ADC-24-7 payload
Undisclosed
Enoblituzumab-ADC-24-7 linker
 ADC Info 
Enoblituzumab-ADC-24-8 [2]
Enoblituzumab-ADC-24-8 payload
Undisclosed
Enoblituzumab-ADC-24-8 linker
 ADC Info 
Enoblituzumab-ADC-24-9 [2]
Enoblituzumab-ADC-24-9 payload
Undisclosed
Enoblituzumab-ADC-24-9 linker
 ADC Info 
Enoblituzumab-ADC-24-10 [2]
Enoblituzumab-ADC-24-10 payload
Undisclosed
Enoblituzumab-ADC-24-10 linker
 ADC Info 
Enoblituzumab-ADC-24-11 [2]
Enoblituzumab-ADC-24-11 payload
Undisclosed
Enoblituzumab-ADC-24-11 linker
 ADC Info 
Enoblituzumab-ADC-24-12 [2]
Enoblituzumab-ADC-24-12 payload
Undisclosed
Enoblituzumab-ADC-24-12 linker
 ADC Info 
Enoblituzumab-ADC-24-13 [2]
Enoblituzumab-ADC-24-13 payload
Undisclosed
Enoblituzumab-ADC-24-13 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-1 [1]
Enoblituzumab-ADC-Tb1-1 payload
Undisclosed
Enoblituzumab-ADC-Tb1-1 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-2 [1]
Enoblituzumab-ADC-Tb1-2 payload
Undisclosed
Enoblituzumab-ADC-Tb1-2 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-3 [1]
Enoblituzumab-ADC-Tb1-3 payload
Undisclosed
Enoblituzumab-ADC-Tb1-3 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-4 [1]
Enoblituzumab-ADC-Tb1-4 payload
Undisclosed
Enoblituzumab-ADC-Tb1-4 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-5 [1]
Enoblituzumab-ADC-Tb1-5 payload
Undisclosed
Enoblituzumab-ADC-Tb1-5 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-6 [1]
Enoblituzumab-ADC-Tb1-6 payload
Undisclosed
Enoblituzumab-ADC-Tb1-6 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-7 [1]
Enoblituzumab-ADC-Tb1-7 payload
Undisclosed
Enoblituzumab-ADC-Tb1-7 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-8 [1]
Enoblituzumab-ADC-Tb1-8 payload
Undisclosed
Enoblituzumab-ADC-Tb1-8 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-9 [1]
Enoblituzumab-ADC-Tb1-9 payload
Undisclosed
Enoblituzumab-ADC-Tb1-9 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-10 [1]
Enoblituzumab-ADC-Tb1-10 payload
Undisclosed
Enoblituzumab-ADC-Tb1-10 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-11 [1]
Enoblituzumab-ADC-Tb1-11 payload
Undisclosed
Enoblituzumab-ADC-Tb1-11 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-12 [1]
Enoblituzumab-ADC-Tb1-12 payload
Undisclosed
Enoblituzumab-ADC-Tb1-12 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-13 [1]
Enoblituzumab-ADC-Tb1-13 payload
Undisclosed
Enoblituzumab-ADC-Tb1-13 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-14 [1]
Enoblituzumab-ADC-Tb1-14 payload
Undisclosed
Enoblituzumab-ADC-Tb1-14 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-15 [1]
Enoblituzumab-ADC-Tb1-15 payload
Undisclosed
Enoblituzumab-ADC-Tb1-15 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-16 [1]
Enoblituzumab-ADC-Tb1-16 payload
Undisclosed
Enoblituzumab-ADC-Tb1-16 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-17 [1]
Enoblituzumab-ADC-Tb1-17 payload
Undisclosed
Enoblituzumab-ADC-Tb1-17 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-18 [1]
Enoblituzumab-ADC-Tb1-18 payload
Undisclosed
Enoblituzumab-ADC-Tb1-18 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-19 [1]
Enoblituzumab-ADC-Tb1-19 payload
Undisclosed
Enoblituzumab-ADC-Tb1-19 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-20 [1]
Enoblituzumab-ADC-Tb1-20 payload
Undisclosed
Enoblituzumab-ADC-Tb1-20 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-21 [1]
Enoblituzumab-ADC-Tb1-21 payload
Undisclosed
Enoblituzumab-ADC-Tb1-21 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-22 [1]
Enoblituzumab-ADC-Tb1-22 payload
Undisclosed
Enoblituzumab-ADC-Tb1-22 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-23 [1]
Enoblituzumab-ADC-Tb1-23 payload
Undisclosed
Enoblituzumab-ADC-Tb1-23 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-24 [1]
Enoblituzumab-ADC-Tb1-24 payload
Undisclosed
Enoblituzumab-ADC-Tb1-24 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-25 [1]
Enoblituzumab-ADC-Tb1-25 payload
Undisclosed
Enoblituzumab-ADC-Tb1-25 linker
 ADC Info 
Enoblituzumab-ADC-Tb1-26 [1]
Enoblituzumab-ADC-Tb1-26 payload
Undisclosed
Enoblituzumab-ADC-Tb1-26 linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HmAb-C-DUBA [20]
Seco-DUBA
Human Deoxyribonucleic acid (hDNA)
Mal-PEG2-Val-Cit-PABA-Cyclization Spacer
 ADC Info 
Hu276 mAb
 Antibody Info 
ADC Name Payload Target Linker ADC Info
CD276 mAb-MMAF [21]
Monomethyl auristatin F
Microtubule (MT)
DBM linker
 ADC Info 
CD276 mAb-IMQ [21]
imiquimod
Toll-like receptor 7 (TLR7); Toll-like receptor 8 (TLR8)
Phosphine-azide
 ADC Info 
CD276 mAb-MMAF/IMQ [21]
Monomethyl auristatin F; imiquimod
Undisclosed
DBM linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb13v1-CZ [19]
huAb13v1-CZ payload
Undisclosed
huAb13v1-CZ linker
 ADC Info 
HuAb13v1-TX [19]
huAb13v1-TX payload
Undisclosed
huAb13v1-TX linker
 ADC Info 
HuAb13v1-TV [19]
huAb13v1-TV payload
Undisclosed
huAb13v1-TV linker
 ADC Info 
HuAb13v1-AAA [19]
huAb13v1-AAA payload
Undisclosed
huAb13v1-AAA linker
 ADC Info 
HuAb13v1-AAD [19]
huAb13v1-AAD payload
Undisclosed
huAb13v1-AAD linker
 ADC Info 
HuAb13v1-WD [19]
huAb13v1-WD payload
Undisclosed
huAb13v1-WD linker
 ADC Info 
HuAb13v1-LB [19]
huAb13v1-LB payload
Undisclosed
huAb13v1-LB linker
 ADC Info 
HuAb13v1-ZT [19]
huAb13v1-ZT payload
Undisclosed
huAb13v1-ZT linker
 ADC Info 
HuAb13v1-ZZ [19]
huAb13v1-ZZ payload
Undisclosed
huAb13v1-ZZ linker
 ADC Info 
HuAb13v1-XW [19]
huAb13v1-XW payload
Undisclosed
huAb13v1-XW linker
 ADC Info 
HuAb13v1-SE [19]
huAb13v1-SE payload
Undisclosed
huAb13v1-SE linker
 ADC Info 
HuAb13v1-SR [19]
huAb13v1-SR payload
Undisclosed
huAb13v1-SR linker
 ADC Info 
HuAb13v1-YG [19]
huAb13v1-YG payload
Undisclosed
huAb13v1-YG linker
 ADC Info 
HuAb13v1-KZ [19]
huAb13v1-KZ payload
Undisclosed
huAb13v1-KZ linker
 ADC Info 
HuAb13v1-WD E2 [19]
huAb13v1-WD E2 payload
Undisclosed
huAb13v1-WD E2 linker
 ADC Info 
HuAb13v1-TX E2 [19]
huAb13v1-TX E2 payload
Undisclosed
huAb13v1-TX E2 linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb18v1-CZ [19]
huAb18v1-CZ payload
Undisclosed
huAb18v1-CZ linker
 ADC Info 
huAb18v10
 Antibody Info 
ADC Name Payload Target Linker ADC Info
HuAb18v10-CZ [19]
huAb18v10-CZ payload
Undisclosed
huAb18v10-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb18v2-CZ [19]
huAb18v2-CZ payload
Undisclosed
huAb18v2-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb18v3-CZ [19]
huAb18v3-CZ payload
Undisclosed
huAb18v3-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb18v4-CZ [19]
huAb18v4-CZ payload
Undisclosed
huAb18v4-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb18v5-CZ [19]
huAb18v5-CZ payload
Undisclosed
huAb18v5-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb18v6-CZ [19]
huAb18v6-CZ payload
Undisclosed
huAb18v6-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb18v7-CZ [19]
huAb18v7-CZ payload
Undisclosed
huAb18v7-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb18v8-CZ [19]
huAb18v8-CZ payload
Undisclosed
huAb18v8-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb18v9-CZ [19]
huAb18v9-CZ payload
Undisclosed
huAb18v9-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb3v1-CZ [19]
huAb3v1-CZ payload
Undisclosed
huAb3v1-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb3v2-CZ [19]
huAb3v2-CZ payload
Undisclosed
huAb3v2-CZ linker
 ADC Info 
huAb3v2.2
 Antibody Info 
ADC Name Payload Target Linker ADC Info
HuAb3v2.2-CZ [19]
huAb3v2.2-CZ payload
Undisclosed
huAb3v2.2-CZ linker
 ADC Info 
huAb3v2.3
 Antibody Info 
ADC Name Payload Target Linker ADC Info
HuAb3v2.3-CZ [19]
huAb3v2.3-CZ payload
Undisclosed
huAb3v2.3-CZ linker
 ADC Info 
huAb3v2.5
 Antibody Info 
ADC Name Payload Target Linker ADC Info
HuAb3v2.5-CZ [19]
huAb3v2.5-CZ payload
Undisclosed
huAb3v2.5-CZ linker
 ADC Info 
HuAb3v2.5-TX [19]
huAb3v2.5-TX payload
Undisclosed
huAb3v2.5-TX linker
 ADC Info 
HuAb3v2.5-TV [19]
huAb3v2.5-TV payload
Undisclosed
huAb3v2.5-TV linker
 ADC Info 
HuAb3v2.5-YY [19]
huAb3v2.5-YY payload
Undisclosed
huAb3v2.5-YY linker
 ADC Info 
HuAb3v2.5-AAA [19]
huAb3v2.5-AAA payload
Undisclosed
huAb3v2.5-AAA linker
 ADC Info 
HuAb3v2.5-AAD [19]
huAb3v2.5-AAD payload
Undisclosed
huAb3v2.5-AAD linker
 ADC Info 
HuAb3v2.5-WD [19]
huAb3v2.5-WD payload
Undisclosed
huAb3v2.5-WD linker
 ADC Info 
HuAb3v2.5-LB [19]
huAb3v2.5-LB payload
Undisclosed
huAb3v2.5-LB linker
 ADC Info 
HuAb3v2.5-ZT [19]
huAb3v2.5-ZT payload
Undisclosed
huAb3v2.5-ZT linker
 ADC Info 
HuAb3v2.5-ZZ [19]
huAb3v2.5-ZZ payload
Undisclosed
huAb3v2.5-ZZ linker
 ADC Info 
HuAb3v2.5-XW [19]
huAb3v2.5-XW payload
Undisclosed
huAb3v2.5-XW linker
 ADC Info 
HuAb3v2.5-SE [19]
huAb3v2.5-SE payload
Undisclosed
huAb3v2.5-SE linker
 ADC Info 
HuAb3v2.5-SR [19]
huAb3v2.5-SR payload
Undisclosed
huAb3v2.5-SR linker
 ADC Info 
HuAb3v2.5-YG [19]
huAb3v2.5-YG payload
Undisclosed
huAb3v2.5-YG linker
 ADC Info 
HuAb3v2.5-KZ [19]
huAb3v2.5-KZ payload
Undisclosed
huAb3v2.5-KZ linker
 ADC Info 
huAb3v2.6
 Antibody Info 
ADC Name Payload Target Linker ADC Info
HuAb3v2.6-CZ [19]
huAb3v2.6-CZ payload
Undisclosed
huAb3v2.6-CZ linker
 ADC Info 
HuAb3v2.6-TX [19]
huAb3v2.6-TX payload
Undisclosed
huAb3v2.6-TX linker
 ADC Info 
HuAb3v2.6-TV [19]
huAb3v2.6-TV payload
Undisclosed
huAb3v2.6-TV linker
 ADC Info 
HuAb3v2.6-YY [19]
huAb3v2.6-YY payload
Undisclosed
huAb3v2.6-YY linker
 ADC Info 
HuAb3v2.6-AAA [19]
huAb3v2.6-AAA payload
Undisclosed
huAb3v2.6-AAA linker
 ADC Info 
HuAb3v2.6-AAD [19]
huAb3v2.6-AAD payload
Undisclosed
huAb3v2.6-AAD linker
 ADC Info 
HuAb3v2.6-WD [19]
huAb3v2.6-WD payload
Undisclosed
huAb3v2.6-WD linker
 ADC Info 
HuAb3v2.6-LB [19]
huAb3v2.6-LB payload
Undisclosed
huAb3v2.6-LB linker
 ADC Info 
HuAb3v2.6-ZT [19]
huAb3v2.6-ZT payload
Undisclosed
huAb3v2.6-ZT linker
 ADC Info 
HuAb3v2.6-ZZ [19]
huAb3v2.6-ZZ payload
Undisclosed
huAb3v2.6-ZZ linker
 ADC Info 
HuAb3v2.6-XW [19]
huAb3v2.6-XW payload
Undisclosed
huAb3v2.6-XW linker
 ADC Info 
HuAb3v2.6-SE [19]
huAb3v2.6-SE payload
Undisclosed
huAb3v2.6-SE linker
 ADC Info 
HuAb3v2.6-SR [19]
huAb3v2.6-SR payload
Undisclosed
huAb3v2.6-SR linker
 ADC Info 
HuAb3v2.6-YG [19]
huAb3v2.6-YG payload
Undisclosed
huAb3v2.6-YG linker
 ADC Info 
HuAb3v2.6-KZ [19]
huAb3v2.6-KZ payload
Undisclosed
huAb3v2.6-KZ linker
 ADC Info 
huAb3v2.8
 Antibody Info 
ADC Name Payload Target Linker ADC Info
HuAb3v2.8-CZ [19]
huAb3v2.8-CZ payload
Undisclosed
huAb3v2.8-CZ linker
 ADC Info 
huAb3v2.9
 Antibody Info 
ADC Name Payload Target Linker ADC Info
HuAb3v2.9-CZ [19]
huAb3v2.9-CZ payload
Undisclosed
huAb3v2.9-CZ linker
 ADC Info 
HuAb3v2.9-TX [19]
huAb3v2.9-TX payload
Undisclosed
huAb3v2.9-TX linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb3v3-CZ [19]
huAb3v3-CZ payload
Undisclosed
huAb3v3-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb3v4-CZ [19]
huAb3v4-CZ payload
Undisclosed
huAb3v4-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb3v5-CZ [19]
huAb3v5-CZ payload
Undisclosed
huAb3v5-CZ linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
HuAb3v6-CZ [19]
huAb3v6-CZ payload
Undisclosed
huAb3v6-CZ linker
 ADC Info 
Ifinatamab
 Antibody Info 
ADC Name Payload Target Linker ADC Info
Ifinatamab deruxtecan
DXd
DNA topoisomerase 1 (TOP1)
Mc-Gly-Gly-Phe-Gly
 ADC Info 
ZA202500415A-ADC Example 4 [22]
NMT inhibitor 1
N-Myristoyltransferase (NMT)
ZA202500415A-ADC-Example-1-Linker
 ADC Info 
SG11202408662TA ADC-C1 [23]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
Mc-Gly-Gly-Phe-Gly
 ADC Info 
SG11202408662TA ADC-C2 [23]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
SG11202408662TA ADC-C3 [23]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
SG11202408662TA ADC-C4 [23]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
SG11202408662TA ADC-C5 [23]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
SG11202408662TA ADC-C6 [23]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
SG11202408662TA ADC-C7 [23]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
SG11202408662TA ADC-C8 [23]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
SG11202408662TA ADC-C9 [23]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
SG11202408662TA ADC-C10 [23]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
SG11202408662TA ADC-C11 [23]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
SG11202408662TA ADC-C12 [23]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
SG11202408662TA ADC-C13 [23]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
SG11202408662TA ADC-C14 [23]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024165045A1 ADC-B [24]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024165045A1 ADC-4 [24]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024165045A1 ADC-5 [24]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024165045A1 ADC-6 [24]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024165045A1 ADC-7 [24]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024165045A1 ADC-8 [24]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024165045A1 ADC-9 [24]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024165045A1 ADC-10 [24]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024165045A1 ADC-11 [24]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024165045A1 ADC-12 [24]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024165045A1 ADC-13 [24]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024165045A1 ADC-14 [24]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
WO2024165045A1 ADC-16 [24]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
CN119317630A ADC-C1 [25]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
Mc-Gly-Gly-Phe-Gly
 ADC Info 
CN119317630A ADC-C2 [25]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
Mc-Gly-Gly-Phe-Gly
 ADC Info 
CN119317630A ADC-C3 [25]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
CN119317630A ADC-C3 Linker
 ADC Info 
CN119317630A ADC-C4 [25]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
CN119317630A ADC-C3 Linker
 ADC Info 
CN119317630A ADC-C5 [25]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
CN119317630A ADC-C5 Linker
 ADC Info 
CN119317630A ADC-C6 [25]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
CN119317630A ADC-C5 Linker
 ADC Info 
CN119317630A ADC-C7 [25]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
CN119317630A ADC-C7 Linker
 ADC Info 
CN119317630A ADC-C8 [25]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
CN119317630A ADC-C8 Linker
 ADC Info 
CN119317630A ADC-C9 [25]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
CN119317630A ADC-C9 Linker
 ADC Info 
CN119317630A ADC-C10 [25]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
CN119317630A ADC-C10 Linker
 ADC Info 
CN119317630A ADC-C11 [25]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
CN119317630A ADC-C11 Linker
 ADC Info 
CN119317630A ADC-C12 [25]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
CN119317630A ADC-C12 Linker
 ADC Info 
CN119317630A ADC-C13 [25]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
CN119317630A ADC-C13 Linker
 ADC Info 
CN119317630A ADC-C14 [25]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
CN119317630A ADC-C14 Linker
 ADC Info 
Mirzotamab
 Antibody Info 
ADC Name Payload Target Linker ADC Info
Mirzotamab clezutoclax
clezutoclax
Bcl-2-like protein 1 (BCL2L1)
Val-Ala dipeptide linker
 ADC Info 
Mirzotamab-ADC-Tb1-1 [1]
Mirzotamab-ADC-Tb1-1 payload
Undisclosed
Mirzotamab-ADC-Tb1-1 linker
 ADC Info 
Mirzotamab-ADC-Tb1-2 [1]
Mirzotamab-ADC-Tb1-2 payload
Undisclosed
Mirzotamab-ADC-Tb1-2 linker
 ADC Info 
Mirzotamab-ADC-Tb1-3 [1]
Mirzotamab-ADC-Tb1-3 payload
Undisclosed
Mirzotamab-ADC-Tb1-3 linker
 ADC Info 
Mirzotamab-ADC-Tb1-4 [1]
Mirzotamab-ADC-Tb1-4 payload
Undisclosed
Mirzotamab-ADC-Tb1-4 linker
 ADC Info 
Mirzotamab-ADC-Tb1-5 [1]
Mirzotamab-ADC-Tb1-5 payload
Undisclosed
Mirzotamab-ADC-Tb1-5 linker
 ADC Info 
Mirzotamab-ADC-Tb1-6 [1]
Mirzotamab-ADC-Tb1-6 payload
Undisclosed
Mirzotamab-ADC-Tb1-6 linker
 ADC Info 
Mirzotamab-ADC-Tb1-7 [1]
Mirzotamab-ADC-Tb1-7 payload
Undisclosed
Mirzotamab-ADC-Tb1-7 linker
 ADC Info 
Mirzotamab-ADC-Tb1-8 [1]
Mirzotamab-ADC-Tb1-8 payload
Undisclosed
Mirzotamab-ADC-Tb1-8 linker
 ADC Info 
Mirzotamab-ADC-Tb1-9 [1]
Mirzotamab-ADC-Tb1-9 payload
Undisclosed
Mirzotamab-ADC-Tb1-9 linker
 ADC Info 
Mirzotamab-ADC-Tb1-10 [1]
Mirzotamab-ADC-Tb1-10 payload
Undisclosed
Mirzotamab-ADC-Tb1-10 linker
 ADC Info 
Mirzotamab-ADC-Tb1-11 [1]
Mirzotamab-ADC-Tb1-11 payload
Undisclosed
Mirzotamab-ADC-Tb1-11 linker
 ADC Info 
Mirzotamab-ADC-Tb1-12 [1]
Mirzotamab-ADC-Tb1-12 payload
Undisclosed
Mirzotamab-ADC-Tb1-12 linker
 ADC Info 
Mirzotamab-ADC-Tb1-13 [1]
Mirzotamab-ADC-Tb1-13 payload
Undisclosed
Mirzotamab-ADC-Tb1-13 linker
 ADC Info 
Mirzotamab-ADC-Tb1-14 [1]
Mirzotamab-ADC-Tb1-14 payload
Undisclosed
Mirzotamab-ADC-Tb1-14 linker
 ADC Info 
Mirzotamab-ADC-Tb1-15 [1]
Mirzotamab-ADC-Tb1-15 payload
Undisclosed
Mirzotamab-ADC-Tb1-15 linker
 ADC Info 
Mirzotamab-ADC-Tb1-16 [1]
Mirzotamab-ADC-Tb1-16 payload
Undisclosed
Mirzotamab-ADC-Tb1-16 linker
 ADC Info 
Mirzotamab-ADC-Tb1-17 [1]
Mirzotamab-ADC-Tb1-17 payload
Undisclosed
Mirzotamab-ADC-Tb1-17 linker
 ADC Info 
Mirzotamab-ADC-Tb1-18 [1]
Mirzotamab-ADC-Tb1-18 payload
Undisclosed
Mirzotamab-ADC-Tb1-18 linker
 ADC Info 
Mirzotamab-ADC-Tb1-19 [1]
Mirzotamab-ADC-Tb1-19 payload
Undisclosed
Mirzotamab-ADC-Tb1-19 linker
 ADC Info 
Mirzotamab-ADC-Tb1-20 [1]
Mirzotamab-ADC-Tb1-20 payload
Undisclosed
Mirzotamab-ADC-Tb1-20 linker
 ADC Info 
Mirzotamab-ADC-Tb1-21 [1]
Mirzotamab-ADC-Tb1-21 payload
Undisclosed
Mirzotamab-ADC-Tb1-21 linker
 ADC Info 
Mirzotamab-ADC-Tb1-22 [1]
Mirzotamab-ADC-Tb1-22 payload
Undisclosed
Mirzotamab-ADC-Tb1-22 linker
 ADC Info 
Mirzotamab-ADC-Tb1-23 [1]
Mirzotamab-ADC-Tb1-23 payload
Undisclosed
Mirzotamab-ADC-Tb1-23 linker
 ADC Info 
Mirzotamab-ADC-Tb1-24 [1]
Mirzotamab-ADC-Tb1-24 payload
Undisclosed
Mirzotamab-ADC-Tb1-24 linker
 ADC Info 
Mirzotamab-ADC-Tb1-25 [1]
Mirzotamab-ADC-Tb1-25 payload
Undisclosed
Mirzotamab-ADC-Tb1-25 linker
 ADC Info 
Mirzotamab-ADC-Tb1-26 [1]
Mirzotamab-ADC-Tb1-26 payload
Undisclosed
Mirzotamab-ADC-Tb1-26 linker
 ADC Info 
Non-pH-B7-H3 Ab
 Antibody Info 
ADC Name Payload Target Linker ADC Info
Non-pH-B7-H3 Ab-Dxd [26]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
Mc-Gly-Gly-Phe-Gly
 ADC Info 
Non-pH-B7-H3 Ab-MMAE [26]
Monomethyl auristatin E
Microtubule (MT)
Mc-Val-Cit-PABC
 ADC Info 
Omburtamab
 Antibody Info 
ADC Name Payload Target Linker ADC Info
Omburtamab-ADC-Tb1-1 [1]
Omburtamab-ADC-Tb1-1 payload
Undisclosed
Omburtamab-ADC-Tb1-1 linker
 ADC Info 
Omburtamab-ADC-Tb1-2 [1]
Omburtamab-ADC-Tb1-2 payload
Undisclosed
Omburtamab-ADC-Tb1-2 linker
 ADC Info 
Omburtamab-ADC-Tb1-3 [1]
Omburtamab-ADC-Tb1-3 payload
Undisclosed
Omburtamab-ADC-Tb1-3 linker
 ADC Info 
Omburtamab-ADC-Tb1-4 [1]
Omburtamab-ADC-Tb1-4 payload
Undisclosed
Omburtamab-ADC-Tb1-4 linker
 ADC Info 
Omburtamab-ADC-Tb1-5 [1]
Omburtamab-ADC-Tb1-5 payload
Undisclosed
Omburtamab-ADC-Tb1-5 linker
 ADC Info 
Omburtamab-ADC-Tb1-6 [1]
Omburtamab-ADC-Tb1-6 payload
Undisclosed
Omburtamab-ADC-Tb1-6 linker
 ADC Info 
Omburtamab-ADC-Tb1-7 [1]
Omburtamab-ADC-Tb1-7 payload
Undisclosed
Omburtamab-ADC-Tb1-7 linker
 ADC Info 
Omburtamab-ADC-Tb1-8 [1]
Omburtamab-ADC-Tb1-8 payload
Undisclosed
Omburtamab-ADC-Tb1-8 linker
 ADC Info 
Omburtamab-ADC-Tb1-9 [1]
Omburtamab-ADC-Tb1-9 payload
Undisclosed
Omburtamab-ADC-Tb1-9 linker
 ADC Info 
Omburtamab-ADC-Tb1-10 [1]
Omburtamab-ADC-Tb1-10 payload
Undisclosed
Omburtamab-ADC-Tb1-10 linker
 ADC Info 
Omburtamab-ADC-Tb1-11 [1]
Omburtamab-ADC-Tb1-11 payload
Undisclosed
Omburtamab-ADC-Tb1-11 linker
 ADC Info 
Omburtamab-ADC-Tb1-12 [1]
Omburtamab-ADC-Tb1-12 payload
Undisclosed
Omburtamab-ADC-Tb1-12 linker
 ADC Info 
Omburtamab-ADC-Tb1-13 [1]
Omburtamab-ADC-Tb1-13 payload
Undisclosed
Omburtamab-ADC-Tb1-13 linker
 ADC Info 
Omburtamab-ADC-Tb1-14 [1]
Omburtamab-ADC-Tb1-14 payload
Undisclosed
Omburtamab-ADC-Tb1-14 linker
 ADC Info 
Omburtamab-ADC-Tb1-15 [1]
Omburtamab-ADC-Tb1-15 payload
Undisclosed
Omburtamab-ADC-Tb1-15 linker
 ADC Info 
Omburtamab-ADC-Tb1-16 [1]
Omburtamab-ADC-Tb1-16 payload
Undisclosed
Omburtamab-ADC-Tb1-16 linker
 ADC Info 
Omburtamab-ADC-Tb1-17 [1]
Omburtamab-ADC-Tb1-17 payload
Undisclosed
Omburtamab-ADC-Tb1-17 linker
 ADC Info 
Omburtamab-ADC-Tb1-18 [1]
Omburtamab-ADC-Tb1-18 payload
Undisclosed
Omburtamab-ADC-Tb1-18 linker
 ADC Info 
Omburtamab-ADC-Tb1-19 [1]
Omburtamab-ADC-Tb1-19 payload
Undisclosed
Omburtamab-ADC-Tb1-19 linker
 ADC Info 
Omburtamab-ADC-Tb1-20 [1]
Omburtamab-ADC-Tb1-20 payload
Undisclosed
Omburtamab-ADC-Tb1-20 linker
 ADC Info 
Omburtamab-ADC-Tb1-21 [1]
Omburtamab-ADC-Tb1-21 payload
Undisclosed
Omburtamab-ADC-Tb1-21 linker
 ADC Info 
Omburtamab-ADC-Tb1-22 [1]
Omburtamab-ADC-Tb1-22 payload
Undisclosed
Omburtamab-ADC-Tb1-22 linker
 ADC Info 
Omburtamab-ADC-Tb1-23 [1]
Omburtamab-ADC-Tb1-23 payload
Undisclosed
Omburtamab-ADC-Tb1-23 linker
 ADC Info 
Omburtamab-ADC-Tb1-24 [1]
Omburtamab-ADC-Tb1-24 payload
Undisclosed
Omburtamab-ADC-Tb1-24 linker
 ADC Info 
Omburtamab-ADC-Tb1-25 [1]
Omburtamab-ADC-Tb1-25 payload
Undisclosed
Omburtamab-ADC-Tb1-25 linker
 ADC Info 
Omburtamab-ADC-Tb1-26 [1]
Omburtamab-ADC-Tb1-26 payload
Undisclosed
Omburtamab-ADC-Tb1-26 linker
 ADC Info 
pH-B7-H3 Ab
 Antibody Info 
ADC Name Payload Target Linker ADC Info
pH-B7-H3 Ab-Dxd [26]
DX-8951 derivative (DXd)
DNA topoisomerase 1 (TOP1)
Mc-Gly-Gly-Phe-Gly
 ADC Info 
pH-B7-H3 Ab-MMAE [26]
Monomethyl auristatin E
Microtubule (MT)
Mc-Val-Cit-PABC
 ADC Info 
Risvutatug
 Antibody Info 
ADC Name Payload Target Linker ADC Info
Risvutatug rezetecan
SHR9265
DNA topoisomerase 1 (TOP1)
Mc-Gly-Gly-Phe-Gly
 ADC Info 
Tambotatug
 Antibody Info 
ADC Name Payload Target Linker ADC Info
Tambotatug pelitecan
YL0010014
DNA topoisomerase 1 (TOP1)
VK*G-NHCH2-O linker
 ADC Info 
ADC Name Payload Target Linker ADC Info
Anti-B7H3 APDC 3f [27]
Kinesin spindle protein (KSP) inhibitor 3f
Kinesin-like protein KIF11 (KIF11)
Open-chain glycine maleimide
 ADC Info 
Anti-B7H3 APDC 3g [27]
Kinesin spindle protein (KSP) inhibitor 3g
Kinesin-like protein KIF11 (KIF11)
Open-chain glycine maleimide
 ADC Info 
Vobramitamab
 Antibody Info 
ADC Name Payload Target Linker ADC Info
Vobramitamab duocarmazine
Seco-DUBA
Human deoxyribonucleic acid (hDNA)
Mal-PEG2-Val-Cit-PABA-Cyclization Spacer
 ADC Info 
MGC026
Exatecan
DNA topoisomerase 1 (TOP1)
Bicyclononyne carbamoyl sulfamide Val-Ala-PABC
 ADC Info 
Undisclosed
 Antibody Info 
ADC Name Payload Target Linker ADC Info
IBI-129
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
YBL-015 [28]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
64Cu-DOTAGA-alphaCD276 mAb [29]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
B7-H3 ADC (Jiangsu hengrui) [30]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
BVD-CD276 [31]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
B7H3-MMAE [32]
Monomethyl auristatin E
Microtubule (MT)
Undisclosed
 ADC Info 
NV106 [33]
Panobinostat
Histone deacetylase 1 (HDAC1)
Undisclosed
 ADC Info 
NV104 [33]
Irinotecan
DNA topoisomerase 1 (TOP1)
Undisclosed
 ADC Info 
NV105 [33]
Temozolomide
Human Deoxyribonucleic acid (hDNA)
Undisclosed
 ADC Info 
ITC-6102RO [34]
Benzodiazepine dimer derivative
Undisclosed
Maleimide-containing OHPAS linker
 ADC Info 
GLR1061 [35]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
antiB7H3 MF6 [36]
MF6
Undisclosed
Undisclosed
 ADC Info 
IL317340A-1 [37]
TW202500135A-1 payload
Undisclosed
Mc-Gly-Gly-Phe-Gly
 ADC Info 
IL317340A-2 1 [37]
TW202500135A-1 payload
Undisclosed
Mc-Gly-Gly-Phe-Gly
 ADC Info 
IL317340A-3 [37]
Undisclosed
Undisclosed
Mc-Gly-Gly-Phe-Gly
 ADC Info 
IL317340A-4 [37]
IL317340A-4payload
Undisclosed
Mc-Gly-Gly-Phe-Gly
 ADC Info 
IL317340A-5 [37]
IL317340A-5payload
Undisclosed
Mc-Gly-Gly-Phe-Gly
 ADC Info 
IL317340A-6 [37]
IL317340A-6payload
Undisclosed
Mc-Gly-Gly-Phe-Gly
 ADC Info 
IL317340A-7 [37]
IL317340A-7payload
Undisclosed
Mc-Gly-Gly-Phe-Gly
 ADC Info 
IL317340A-8 [37]
Topo1 inhibitor F
DNA topoisomerase I (TOP1)
Mc-Gly-Gly-Phe-Gly
 ADC Info 
IL317340A-9 [37]
IL317340A-9payload
Undisclosed
Mc-Gly-Gly-Phe-Gly
 ADC Info 
IL317340A-10 [37]
IL317340A-10payload
Undisclosed
Mc-Gly-Gly-Phe-Gly
 ADC Info 
IL317340A-11 [37]
Undisclosed
Undisclosed
Mc-Gly-Gly-Phe-Gly
 ADC Info 
IL317340A-12 [37]
Undisclosed
Undisclosed
Mc-Gly-Gly-Phe-Gly
 ADC Info 
IL317340A-13 [37]
TW202500135A-1 payload
Undisclosed
Mc-Gly-Gly-Phe-Gly
 ADC Info 
IL317340A-14 [37]
TW202500135A-1 payload
Undisclosed
Mc-Gly-Gly-Phe-Gly
 ADC Info 
Production of the antibody-drug conjugate (4) [38]
undisclosed
Undisclosed
Undisclosed
 ADC Info 
References
Ref 1 Bioactive substance conjugate, preparation method therefor and use thereof; 2022-08-18.
Ref 2 Ligand-drug conjugate of exatecan analogue, preparation method therefor and application thereof; 2020-04-02.
Ref 3 Design, Synthesis, and Evaluation of Camptothecin-Based Antibody-Drug Conjugates with High Hydrophilicity and Structural Stability
Ref 4 Bliss Biopharmaceutical company product pipeline
Ref 5 Anti-b7h3 antibody-drug conjugate and use thereof
Ref 6 Clinical Trial Application for 7MW3711 - an Innovative Drug Developed by Mabwell's ADC Platform, Accepted by NMPA.
Ref 7 BGB-C354, a novel B7H3 ADC with high DAR stability and strong bystander effect, demonstrates robust antitumor activity in preclinical models
Ref 8 Multi-payload antibody-drug conjugates and their preparation methods and uses
Ref 9 A CD276-Targeted Antibody-Drug Conjugate to Treat Non-Small Lung Cancer (NSCLC)
Ref 10 Anti-b7h3 antibody-exatecan analog conjugate and medicinal use thereof; 2020-04-02.
Ref 11 The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models. Clin Cancer Res. 2021 May 15;27(10):2938-2946. doi: 10.1158/1078-0432.CCR-20-4221. Epub 2021 Feb 22.
Ref 12 A Novel NAMPT Inhibitor-Based Antibody-Drug Conjugate Payload Class for Cancer Therapy. Bioconjug Chem. 2022 Jun 15;33(6):1210-1221.
Ref 13 Novel B7-H3- binding molecule, its antibody drug conjugate and its application method.
Ref 14 Antibody-drug conjugates and uses thereof
Ref 15 Development of a MMAE-based antibody-drug conjugate targeting B7-H3 for glioblastoma
Ref 16 PanRAS inhibitor antibody-drug conjugates and methods of use thereof
Ref 17 Drug conjugates and uses thereof
Ref 18 Antibody-drug conjugates containing toxins with polar groups and uses thereof
Ref 19 Anti-b7-h3 antibodies and antibody drug conjugates; 2018-03-08.
Ref 20 Novel b7-h3 binding molecules, antibody drug conjugates thereof and methods of use thereof; 2017-10-19.
Ref 21 A Dual-Payload Antibody-Drug Conjugate Targeting CD276/B7-H3 Elicits Cytotoxicity and Immune Activation in Triple-Negative Breast Cancer
Ref 22 Antibody drug conjugate comprising NMT inhibitor and its use
Ref 23 Antibody drug conjugates
Ref 24 Self-stabilizing linker conjugates
Ref 25 Antibody-drug complexes
Ref 26 A next generation ADC: AR153, pH-dependent anti-B7H3 MMAE
Ref 27 Antibody-Prodrug Conjugates with KSP Inhibitors and Legumain-Mediated Metabolite Formation. Chemistry. 2019 Jun 21;25(35):8208-8213. doi: 10.1002/chem.201900441. Epub 2019 Apr 15.
Ref 28 Y-Biologics biotechnology company product pipeline
Ref 29 Introduction to basic information on ADC drug 64Cu-DOTAGA-alphaCD276 mAb (Provenance).
Ref 30 Introduction to basic information on ADC drug B7-H3 ADC (Jiangsu hengrui).
Ref 31 Biomed valley discoveries product pipeline
Ref 32 Anwita biosciences product pipeline
Ref 33 Nanovalent pharmaceuticals product pipeline
Ref 34 ITC-6102RO, a novel B7-H3 antibody-drug conjugate, exhibits potent therapeutic effects against B7-H3 expressing solid tumors
Ref 35 Preclinical characterization of GLR1061, a B7H3-targeted ADC with a novel DNA topoisomerase I inhibitor, demonstrated superior bystander effect to overcome tumor heterogeneity
Ref 36 Design and synthesis of the novel camptothecin analog MF-6 for application into site-specific antibody-drug conjugate
Ref 37 Anti-B7-H3 antibody-drug conjugates and uses thereof
Ref 38 Combination of antibody-drug conjugate with anti-SIRPα antibody