General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0LDEJY
ADC Name
iTC-6146RO
Synonyms
ITC-6146RO
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Organization
IntoCell (Originator)
Drug Status
Phase 1
Antibody Name
Anti-B7H3 antibody
 Antibody Info 
Antigen Name
CD276 antigen (CD276); Hepatocyte growth factor receptor (MET)
 Antigen Info 
Payload Name
Duocarmycin derivative
 Payload Info 
Therapeutic Target
Human deoxyribonucleic acid (hDNA)
 Target Info 
Linker Name
Self-immolative OHPAS linker
 Linker Info 
Conjugate Type
Undisclosed
The indication landscape of This ADC(2027 Update)
The clinical trial pipeline of This ADC(2027 Update)
Indication Phase 1 Phase 1/2 Phase 2 Phase 2/3 Phase 3 New Drug Application Approved
Breast cancer
1 Trials
Trial ID
NCT07423117
Lung cancer
1 Trials
Trial ID
NCT07423117
Prostate cancer
1 Trials
Trial ID
NCT07423117
Unspecific solid tumor
1 Trials
Trial ID
NCT07423117