Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0UPDIB
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| ADC Name |
M276-SL-PBD
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| Synonyms |
M276 SL PBD
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| Organization |
Children's Hospital of Philadelphia
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| Drug Status |
Clinical candidate
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| Indication |
In total 1 Indication(s)
Solid tumors [ICD11:2A00-2A0Z|2B50-2F9Z]
Clinical candidate
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| Drug-to-Antibody Ratio |
2
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| Antibody Name |
Anti-CD276 mAb m276-SL
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Antibody Info | ||||
| Antigen Name |
CD276 antigen (CD276)
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Antigen Info | ||||
| Payload Name |
PBD dimer
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Payload Info | ||||
| Therapeutic Target |
Human Deoxyribonucleic acid (hDNA)
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Target Info | ||||
| Linker Name |
Mc-Val-Ala
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Linker Info | ||||
| Conjugate Type |
Engineered m276-SL antibody, S239C site for site-specific conjugating, Michael addition.
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