Antibody Information

General Information of This Antibody
Antibody ID
ANI0KQZUA
Antibody Name
chAb4
Antibody Type
Monoclonal antibody (mAb)
Antibody Subtype
Chimeric IgG1-kappa
Antigen Name
CD276 antigen (CD276)
  Antigen Info 
Each Antibody-drug Conjugate Related to This Antibody
Full Information of The Activity Data of The ADC(s) Related to This Antibody
chAb4-CZ [Investigative]
 ADC Info 
Revealed Based on the Cell Line Data
Click To Hide/Show 1 Activity Data Related to This Level
Experiment 1 Reporting the Activity Date of This ADC [1]
Efficacy Data Half Maximal Inhibitory Concentration (IC50)
0.26 nM
Positive CD276 expression (CD276 +++/++)
Method Description
Chimra IgG1 variants were conjugated to the CZ synthon and tested for cytotoxicity in HCC38 cell line.
In Vitro Model Breast ductal carcinoma HCC38 cells CVCL_1267
References
Ref 1 Anti-b7-h3 antibodies and antibody drug conjugates; 2018-03-08.

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