Antigen ID	TAR0WTBIA
Antigen Name	V-type immunoglobulin domain-containing suppressor of T-cell activation (VSIR)
Gene Name	VSIR
Synonym	C10orf54; SISP1; VISTA
Sequence	MGVPTALEAGSWRWGSLLFALFLAASLGPVAAFKVATPYSLYVCPEGQNVTLTCRLLGPV DKGHDVTFYKTWYRSSRGEVQTCSERRPIRNLTFQDLHLHHGGHQAANTSHDLAQRHGLE SASDHHGNFSITMRNLTLLDSGLYCCLVVEIRHHHSEHRVHGAMELQVQTGKDAPSNCVV YPSSSQDSENITAAALATGACIVGILCLPLILLLVYKQRQAASNRRAQELVRMDSNIQGI ENPGFEASPPAQGIPEAKVRHPLSYVAQRQPSESGRHLLSEPSTPLSPPGPGDVFFPSLD PVPDSPNFEVI     Click to Show/Hide
Function	FUNCTION: Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14-mediated MMP2 activation (PubMed:20666777). {ECO:0000250|UniProtKB:Q9D659, ECO:0000269|PubMed:20666777, ECO:0000269|PubMed:24691993}.     Click to Show/Hide
Uniprot Entry	VISTA_HUMAN
HGNC ID	HGNC:30085 ,
KEGG ID	hsa:64115 ,

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	CN114230664B 146C: DBM- (C6)-MMAF	Monomethyl auristatin F	Microtubule (MT)	DBM linker	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	CN114230664B 164A: DBM- (C6)-MMAF	Monomethyl auristatin F	Microtubule (MT)	DBM linker	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	CN114230664B 175A: DBM- (C6)-MMAF	Monomethyl auristatin F	Microtubule (MT)	DBM linker	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	CN114230664B 208A: DBM- (C6)-MMAF	Monomethyl auristatin F	Microtubule (MT)	DBM linker	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	CN114230664B 215A: DBM- (C6)-MMAF	Monomethyl auristatin F	Microtubule (MT)	DBM linker	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	CN114230664B 230A: DBM- (C6)-MMAF	Monomethyl auristatin F	Microtubule (MT)	DBM linker	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	CN114230664B 259A: DBM- (C6)-MMAF	Monomethyl auristatin F	Microtubule (MT)	DBM linker	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	CN114230664B 305A: DBM- (C6)-MMAF	Monomethyl auristatin F	Microtubule (MT)	DBM linker	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	CN114230664B 353A: DBM- (C6)-MMAF	Monomethyl auristatin F	Microtubule (MT)	DBM linker	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	CN114230664B 53A: DBM- (C6)-MMAF	Monomethyl auristatin F	Microtubule (MT)	DBM linker	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	CN114230664B 5B: DBM- (C6)-MMAF	Monomethyl auristatin F	Microtubule (MT)	DBM linker	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	CN114230664B 76E1: DBM- (C6)-MMAF	Monomethyl auristatin F	Microtubule (MT)	DBM linker	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	cN116096413A 767-IgG1.3A	INX-A-2 payload	Undisclosed	INX-A-3 linker	[2]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	lFD-200	Undisclosed	Glucocorticoid receptor (NR3C1)	Undisclosed

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	C1.18 DBM- (C6)-MMAF	Monomethyl auristatin F	Microtubule (MT)	DBM linker	[1]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	iNX-200A 7.8	INX-A-2 payload	Undisclosed	INX-A-3 linker	[2]
ADC Info	iNX-200A 8	INX-A-2 payload	Undisclosed	INX-A-3 linker	[2]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	iNX-201A	INX-A-2 payload	Undisclosed	INX-A-3 linker	[2]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	iNX-210A	INX-A-2 payload	Undisclosed	INX-A-3 linker	[2]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	INX201J	Cpd 2	Glucocorticoid receptor (GR)	Cys linker	[3]
ADC Info	INX201N	INX-SM-1 payload	Undisclosed	JP2024502360A5 INX201N Linker	[3]
ADC Info	INX201O	INX-SM-4 payload	Undisclosed	JP2024502360A5 INX201N Linker	[3]
ADC Info	INX201P	INX-SM-3 payload	Undisclosed	JP2024502360A5 INX201N Linker	[3]
ADC Info	INX201V	INX-SM-3 payload	Undisclosed	JP2024502360A5 INX201N Linker	[3]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	INX231P	INX-SM-3 payload	Undisclosed	Cys linker	[3]
ADC Info	INX231V	INX-SM-3 payload	Undisclosed	Cys linker	[3]
ADC Info	INX231J	Cpd 2	Glucocorticoid receptor (GR)	Cys linker	[3]
ADC Info	INX231R	INX-SM-3 payload	Undisclosed	JP2024502360A5 INX231R Linker	[3]
ADC Info	INX231S	INX-SM-24 payload	Undisclosed	JP2024502360A5 INX201N Linker	[3]
ADC Info	INX231W	INX-SM-3 payload	Undisclosed	JP2024502360A5 INX231W Linker	[3]
ADC Info	INX231A7	INX-SM-3 payload	Undisclosed	JP2024502360A5 INX201N Linker	[3]
ADC Info	INX231A23	INX-SM-25 payload	Undisclosed	JP2024502360A5 INX201N Linker	[3]
ADC Info	INX231A12	INX-SM-25 payload	Undisclosed	JP2024502360A5 INX201N Linker	[3]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	INX233P	INX-SM-3 payload	Undisclosed	JP2024502360A5 INX201N Linker	[3]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	INX234A11	INX-SM-3 payload	Undisclosed	Cys linker	[3]
ADC Info	INX234V	INX-SM-3 payload	Undisclosed	Cys linker	[3]
ADC Info	INX234J	Cpd 2	Glucocorticoid receptor (GR)	JP2024502360A5 INX201N Linker	[3]
ADC Info	INX234P	INX-SM-3 payload	Undisclosed	JP2024502360A5 INX201N Linker	[3]
ADC Info	INX234A4	INX-SM-43 payload	Undisclosed	JP2024502360A5 INX201N Linker	[3]
ADC Info	INX234A13	INX-SM-34 payload	Undisclosed	JP2024502360A5 INX201N Linker	[3]
ADC Info	INX234A1	INX-SM-35 payload	Undisclosed	JP2024502360A5 INX201N Linker	[3]
ADC Info	INX234A9	INX-SM-46 payload	Undisclosed	JP2024502360A5 INX201N Linker	[3]

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	INX240J	Cpd 2	Glucocorticoid receptor (GR)	JP2024502360A5 INX201N Linker	[3]

Ref 1	Anti-C10orf54 antibodies and uses thereof
Ref 2	Anti-human VISTA antibodies and uses thereof
Ref 3	New stelloid payloads, stelloid linkers, adcs, and their use