Antibody Information
General Information of This Antibody
| Antibody ID | ANTI0RYQLL |
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| Antibody Name | 76E1 |
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| Synonyms |
76E1
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| Antigen Name | V-type immunoglobulin domain-containing suppressor of T-cell activation (VSIR) |
Antigen Info | ||||
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Each Antibody-drug Conjugate Related to This Antibody
Full Information of The Activity Data of The ADC(s) Related to This Antibody
CN114230664B 76E1: DBM- (C6)-MMAF [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
0.06 nM
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High Nectin-4 expression (Nectin-4 +++) | ||
| Method Description |
NEC49-9-A was tested in MDA-MB-468,1×106/ml,1h
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| In Vitro Model | Breast adenocarcinoma | MDA-MB-468 cells | CVCL_0419 | ||
| Experiment 2 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
0.07 nM
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High Nectin-4 expression (Nectin-4 +++) | ||
| Method Description |
NEC49-9-A was tested in T47D,1×106/ml,1h
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| In Vitro Model | Invasive breast carcinoma of no special type | T47D cells | CVCL_0553 | ||
| Experiment 3 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
0.78 nM
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High Nectin-4 expression (Nectin-4 +++) | ||
| Method Description |
NEC49-9-A was tested in Nectin4-CHOK1,1×106/ml,1h
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| In Vitro Model | Normal | CHOK1 cells | CVCL_0214 | ||
References