Antigen Information

General Information of This Antigen
Antigen ID
TAR0GJMYC
Antigen Name
Haptoglobin-hemoglobin receptor (Tb06.28F21.220)
Gene Name
Tb06.28F21.220
Gene ID
3657679
Sequence
>tr|Q581F2|Q581F2_TRYB2Haptoglobin-hemoglobinreceptorOS=Tryp
anosomabruceibrucei(strain927/4GUTat10.1)OX=185431GN=Tb06.28
F21.220PE=1SV=1MEKPSCRGAGWAQLLWCYGTCCALLLRLIVEASQAAEGLKTKDEV
EKACHLAQQLKEVSITLGVIYRTTERHSVQVEAHKTAIDKHADAVSRAVEALTRVDVALQ
RLKELGKANDTKAVKIIENITSARENLALFNNETQAVLTARDHVHKHRAAALQGWSDAKE
KGDAAAEDVWVLLNAAKKGNGSADVKAAAEKCSRYSSSSTSETELQKAIDAAANVGGLSA
HKSKYGDVLNKFKLSNASVGAVRDTSGRGGKHMEKVNNVAKLLKDAEVSLAAAAAEIEEV
KNAHETKAQEEMKRNGNPIENESETNSGGNAESQGNGDREDKNDEQQQVDEEETKVENGS
SEEGSCCGNESNGPHVMKKRHGVEGPRPVDVVSGFRSYASASFALLSLVRVGMLQVVV

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Uniprot Entry
Q581F2_TRYB2
KEGG ID
tbr:Tb927.6.440
Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
Anti-HpHbR mAb Tb074
 Antibody Info 
ADC Info ADC Name Payload Target Linker Ref
 ADC Info 
Tb074-SG3376
PBD dimer SG3552
Human Deoxyribonucleic acid (hDNA)
Mal-PEG4
 [1]
Anti-HpHbR mAb Tb085
 Antibody Info 
ADC Info ADC Name Payload Target Linker Ref
 ADC Info 
Tb085-SG3376
PBD dimer SG3552
Human Deoxyribonucleic acid (hDNA)
Mal-PEG4
 [1]
References
Ref 1 A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis. PLoS Negl Trop Dis. 2019 May 23;13(5):e0007373. doi: 10.1371/journal.pntd.0007373. eCollection 2019 May.

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