Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0YFPJB
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| ADC Name |
OBA01
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| Synonyms |
ADC-MMAE/F 2+2
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| Drug Status |
Investigative
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| Indication |
In total 3 Indication(s)
Acute lymphoblastic leukemia [ICD11:2B33]
Investigative
Acute myeloid leukaemia [ICD11:2A60]
Investigative
Burkitt lymphoma [ICD11:2A85]
Investigative
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| Drug-to-Antibody Ratio |
4
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| Structure |
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| Antibody Name |
Zaptuzumab
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Antibody Info | ||||
| Antigen Name |
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
PY-MAA-Val-Cit-PABC
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Linker Info | ||||
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