Antibody-drug Conjugate Information

General Information of This Antibody-drug Conjugate (ADC)

ADC ID	DRG0TREVJ
ADC Name	MEDI-7247
Synonyms	MEDI-7247; MEDI 7247; MEDI7247 Click to Show/Hide
Organization	AstraZeneca PLC
Drug Status	Phase 1 (Terminated)
Indication	In total 8 Indication(s) Acute myeloid leukaemia Phase 1 Clinical Trial Colorectal cancer Phase 1 Clinical Trial Diffuse large B-cell lymphoma Phase 1 Clinical Trial Head and neck cancer Phase 1 Clinical Trial Lung cancer Phase 1 Clinical Trial Multiple myeloma Phase 1 Clinical Trial Pancreatic cancer Phase 1 Clinical Trial Prostate cancer Phase 1 Clinical Trial
Drug-to-Antibody Ratio	2
	3D MOL	2D MOL
Antibody Name	Idactamab		Antibody Info
Antigen Name	Neutral amino acid transporter B(0) (SLC1A5)		Antigen Info
Payload Name	SG3199		Payload Info
Therapeutic Target	Human Deoxyribonucleic acid (hDNA)		Target Info
Linker Name	Mal-PEG8-Val-Ala-PABC		Linker Info
Conjugate Type	Non-natural Amino Acids
Combination Type	tesirine