Antigen Information
General Information of This Antigen
| Antigen ID | TAR0YXJAE |
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|---|---|---|---|---|---|---|
| Antigen Name | Amino acid transporter (ASCT2) |
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| Gene Name | ASCT2 |
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| Gene ID | ||||||
| Sequence |
MVADPPKGDPKGFSAAAEPTANGDPVAVPVDHHVPAPGGGCGSPQQVRRCLRANLLVLLT
VLAVLAGVALGLGMSGAGGRHALDPAHLVAFSFPGELLLRLLRMIILPLVVCSLVGGAAS LDPSSLGRLGAWALLFFLVTTLLSSALGVALALVLQPGATAAAINASVGATRAAEATPTK EVLDSFLDLLRNIFPSNLVSAAFRSYSTQWEMKWVDEIQNRTSVKTAGEVEGMNILGLVV FAIVFGVALRKLGPEGELLIRFFNSFNDATMVLVSWIMWYAPVGILFLVASKIMEMDDVG LLFAVLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGILTPLATAFGTSSSSAT LPLMMKFVEEKNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLNEKPLDFVKIII ILVTATASSVGAAGIPAGGVLTLAIILEAVSLPVHDLSLILAVDWLVDRFCTVINVEGDA FGAGLLQSYAARAEVKSSVPELLQVKSKTPLAPTEEGNPLLRRCPGPPGDAHTCEKESVM Click to Show/Hide
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| Family | Dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family |
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| Uniprot Entry | ||||||
| KEGG ID | ||||||
Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
huASCT2 17c10 mAb
| ADC Info | ADC Name | Payload | Target | Linker | Ref |
|---|---|---|---|---|---|
EP4471061A1 17c10_MC-Dxd |
DX-8951 derivative (DXd) |
DNA topoisomerase 1 (TOP1) |
6-Maleimidocaproic acid |
[1] | |
ICT_MC-Dxd (Isotype control) |
DX-8951 derivative (DXd) |
DNA topoisomerase 1 (TOP1) |
6-Maleimidocaproic acid |
[1] | |
EP4471061A1 17c10_betaGlu-EXA-2 |
Undisclosed |
Undisclosed |
Undisclosed |
[1] | |
ICT_betaGlu-EXA-2 |
Undisclosed |
Undisclosed |
Undisclosed |
[1] | |
EP4471061A1 MC_Dxd |
DX-8951 derivative (DXd) |
DNA topoisomerase 1 (TOP1) |
6-Maleimidocaproic acid |
[1] | |
betaGlu-EXA-2 |
Undisclosed |
Undisclosed |
Undisclosed |
[1] |
Idactamab
| ADC Info | ADC Name | Payload | Target | Linker | Ref |
|---|---|---|---|---|---|
MEDI7247 |
SG3199 (SC-DR002) |
Human deoxyribonucleic acid (hDNA) |
Mal-PEG8-Val-Ala-PABC |