Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0OGJKO
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| ADC Name |
40410803 16B10-DM1
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| Synonyms |
16B10-DM1
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| Organization |
Instituto de Biología Molecular y Celular del Cáncer - CSIC.; CIBERONC.; IBSAL.; Catalan Institute of Oncology.; Institut d'Investigació Biomèdica de Bellvitge - IDIBELL - ONCOBELL.
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| Drug Status |
Investigative
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| Structure |
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| Antibody Name |
16B10
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Antibody Info | ||||
| Antigen Name |
Transforming growth factor alpha (TGFA)
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Antigen Info | ||||
| Payload Name |
Mertansine DM1
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Succinimidyl-4- (N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)
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Linker Info | ||||
| Conjugate Type |
Site-specific bioconjugation via AJICAP-M at K248.
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