Antigen Information
General Information of This Antigen (ID: TAR0YEKMX)
| Antigen Name | Transforming growth factor alpha (TGFA) |
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| Gene Name | TGFA |
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| Gene ID | ||||||
| Synonym | TGFA |
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| Sequence |
MVPSAGQLALFALGIVLAACQALENSTSPLSADPPVAAAVVSHFNDCPDSHTQFCFHGTC
RFLVQEDKPACVCHSGYVGARCEHADLLAVVAASQKKQAITALVVVSIVALAVLIITCVL IHCCQVRKHCEWCRALICRHEKPSALLKGRTACCHSETVV Click to Show/Hide
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| Function |
FUNCTION: TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
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| Uniprot Entry | ||||||
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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
|---|---|---|---|---|
16B10
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
40410803 16B10-DM1
[1]
|
Mertansine DM1 |
Microtubule (MT) |
Succinimidyl-4- (N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC) |
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|
40410803 16B10-Dxd
[1]
|
DX-8951 derivative (DXd) |
DNA topoisomerase 1 (TOP1) |
Mc-Gly-Gly-Phe-Gly |
|
|
40410803 16B10-MMAF
[1]
|
Monomethyl auristatin F |
Microtubule (MT) |
Mc-Val-Cit-PABC |
5F1
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
40410803 5F1-DM1
[1]
|
Mertansine DM1 |
Microtubule (MT) |
Succinimidyl-4- (N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC) |
|
|
40410803 5F1-Dxd
[1]
|
DX-8951 derivative (DXd) |
DNA topoisomerase 1 (TOP1) |
Mc-Gly-Gly-Phe-Gly |
|
|
40410803 5F1-MMAF
[1]
|
Monomethyl auristatin F |
Microtubule (MT) |
Mc-Val-Cit-PABC |
References