Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0HVSQZ
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| ADC Name |
BT062-SPP-DM1
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| Synonyms |
BT062 SPP DM1
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Multiple myeloma [ICD11:2A83]
Investigative
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| Drug-to-Antibody Ratio |
3.5
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| Structure |
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| Antibody Name |
Indatuximab
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Antibody Info | ||||
| Antigen Name |
Syndecan-1 (SDC1)
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Antigen Info | ||||
| Payload Name |
Mertansine DM1
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
N-succinimidyl 4-(2-pyridyldithio) pentanoate (SPP)
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Linker Info | ||||
| Conjugate Type |
Lysine residue on the antibody is conjugated via an amide bond to the linker-payload moiety.
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| Combination Type |
Mertansine
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