Antigen Information
General Information of This Antigen (ID: TAR0GIFMP)
| Antigen Name | G-protein coupled receptor 20 (GPR20) |
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|---|---|---|---|---|---|---|
| Gene Name | GPR20 |
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| Gene ID | ||||||
| Sequence |
MPSVSPAGPSAGAVPNATAVTTVRTNASGLEVPLFHLFARLDEELHGTFPGLWLALMAVH
GAIFLAGLVLNGLALYVFCCRTRAKTPSVIYTINLVVTDLLVGLSLPTRFAVYYGARGCL RCAFPHVLGYFLNMHCSILFLTCICVDRYLAIVRPEGSRRCRQPACARAVCAFVWLAAGA VTLSVLGVTGSRPCCRVFALTVLEFLLPLLVISVFTGRIMCALSRPGLLHQGRQRRVRAM QLLLTVLIIFLVCFTPFHARQVAVALWPDMPHHTSLVVYHVAVTLSSLNSCMDPIVYCFV TSGFQATVRGLFGQHGEREPSSGDVVSMHRSSKGSGRHHILSAGPHALTQALANGPEA Click to Show/Hide
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| Family | G-protein coupled receptor 1 family |
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| Function |
Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP.
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| Uniprot Entry | ||||||
| HGNC ID | ||||||
| KEGG ID | ||||||
Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
|---|---|---|---|---|
04-046Ch
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
WO2018135501A1 ADC-1
[1]
|
WO2018135501A1_ADC-1 payload |
Undisclosed |
WO2018135501A1_ADC-1 linker |
|
|
WO2018135501A1 ADC-2
[1]
|
WO2018135501A1_ADC-2 payload |
Undisclosed |
WO2018135501A1_ADC-2 linker |
Anti-GPR20 antibody
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
DS-6157
|
DXd |
DNA topoisomerase 1 (TOP1) |
Mc-Gly-Gly-Phe-Gly |
h046-H10/L1
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
WO2018135501A1 ADC-11
[1]
|
WO2018135501A1_ADC-11 payload |
Undisclosed |
WO2018135501A1_ADC-11 linker |
h046-H10/L6
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
WO2018135501A1 ADC-12
[1]
|
WO2018135501A1_ADC-12 payload |
Undisclosed |
WO2018135501A1_ADC-12 linker |
h046-H4b/L7
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
WO2018135501A1 ADC-3
[1]
|
WO2018135501A1_ADC-3 payload |
Undisclosed |
WO2018135501A1_ADC-3 linker |
|
|
WO2018135501A1 ADC-4
[1]
|
WO2018135501A1_ADC-4 payload |
Undisclosed |
WO2018135501A1_ADC-4 linker |
|
|
WO2018135501A1 ADC-7
[1]
|
WO2018135501A1_ADC-7 payload |
Undisclosed |
WO2018135501A1_ADC-7 linker |
h046-H4e/L7
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
WO2018135501A1 ADC-13
[1]
|
WO2018135501A1_ADC-13 payload |
Undisclosed |
WO2018135501A1_ADC-13 linker |
|
|
WO2018135501A1 ADC-14
[1]
|
WO2018135501A1_ADC-14 payload |
Undisclosed |
WO2018135501A1_ADC-14 linker |
h046-H5b/L2
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
WO2018135501A1 ADC-5
[1]
|
WO2018135501A1_ADC-5 payload |
Undisclosed |
WO2018135501A1_ADC-5 linker |
|
|
WO2018135501A1 ADC-8
[1]
|
WO2018135501A1_ADC-8 payload |
Undisclosed |
WO2018135501A1_ADC-8 linker |
h046-H8/L1
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
WO2018135501A1 ADC-10
[1]
|
WO2018135501A1_ADC-10 payload |
Undisclosed |
WO2018135501A1_ADC-10 linker |
h046-Hwt/L6
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
WO2018135501A1 ADC-6
[1]
|
WO2018135501A1_ADC-6 payload |
Undisclosed |
WO2018135501A1_ADC-6 linker |
|
|
WO2018135501A1 ADC-9
[1]
|
WO2018135501A1_ADC-9 payload |
Undisclosed |
WO2018135501A1_ADC-9 linker |
Undisclosed
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
Production of the antibody-drug conjugate (5)
[2]
|
undisclosed |
Undisclosed |
Undisclosed |
References