Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0ZTLWT
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| ADC Name |
huDS6v1.21-DM4
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| Synonyms |
huDS6v1.21 DM4
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| Organization |
Sanofi SA
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| Drug Status |
Investigative
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| Indication |
In total 5 Indication(s)
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| Drug-to-Antibody Ratio |
3-4
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| Structure |
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| Antibody Name |
huDS6v1.21
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Antibody Info | ||||
| Antigen Name |
Mucin-1 (MUC1)
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Antigen Info | ||||
| Payload Name |
Mertansine DM4
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
N-succinimidyl 4-(2-pyridyldithio) butanoate (SPDB)
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Linker Info | ||||
| Conjugate Type |
Random conjugation through nucleophilic lysines.
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| Combination Type |
Ravtansine
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