Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0YRMSC
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| ADC Name |
aCEA5-AAN-exatecan
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| Synonyms |
aCEA5-AAN-exatecan
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| Organization |
Bioorganic Chemistry, University of Bayreuth.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
7.7
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| Structure |
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| Antibody Name |
huIgG1 LALA
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Antibody Info | ||||
| Antigen Name |
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5)
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Antigen Info | ||||
| Payload Name |
Exatecan
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
MC-AAN
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
MC-AAN-exatecan
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