Linker Information
General Information of This Linker
| Linker ID |
LIN0FAVRH
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| Linker Name |
MC-AAN
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C24H30N6O8
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| Isosmiles |
O=C(N[C@@H](C)C(N[C@H](C(N[C@@H](CC(N)=O)C(NC1=CC=C(C=C1)CO)=O)=O)C)=O)CCN2C(C=CC2=O)=O
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| InChI |
InChI=1S/C24H30N6O8/c1-13(26-19(33)9-10-30-20(34)7-8-21(30)35)22(36)27-14(2)23(37)29-17(11-18(25)32)24(38)28-16-5-3-15(12-31)4-6-16/h3-8,13-14,17,31H,9-12H2,1-2H3,(H2,25,32)(H,26,33)(H,27,36)(H,28,38)(H,29,37)/t13-,14-,17-/m0/s1
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| InChIKey |
ZDZKHNKWSXHNGQ-ZQIUZPCESA-N
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| Pharmaceutical Properties |
Molecule Weight
|
530.538
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Polar area
|
217.1
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Complexity
|
1065.352422
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xlogp Value
|
-2.1979
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Heavy Count
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38
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Rot Bonds
|
13
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Hbond acc
|
8
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker