Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0YMBRV
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| ADC Name |
CD22 Nanobody DM1
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| Synonyms |
CD22 Nanobody DM1
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| Organization |
Pasteur Institute of Iran.; Shahid Beheshti University.; Royan Institute for Stem Cell Biology and Technology.
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| Drug Status |
Investigative
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| Structure |
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| Antibody Name |
CD22 Nanobody
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Antibody Info | ||||
| Antigen Name |
B-cell receptor CD22 (CD22)
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Antigen Info | ||||
| Payload Name |
Mertansine DM1
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Payload Info | ||||
| Payload Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Succinimidyl-4- (N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
SMCC-DM1
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