Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0XRKKV
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| ADC Name |
WO2020252015A1 ADCLP-28
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| Synonyms |
ADCLP-28
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| Organization |
SUTRO BIOPHARMA, INC.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
1-10
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| Structure |
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| Antibody Name |
mAb42
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Antibody Info | ||||
| Antigen Name |
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (ROR1)
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Antigen Info | ||||
| Payload Name |
PNU-159682
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 2-alpha (TOP2A)
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Target Info | ||||
| Linker Name |
DBCO-nAA-sidechain PEG12
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Linker Info | ||||
| Conjugate Type |
Site-specific conjugation through the Sortase A at the C-terminal of heavy and light chain.
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| Combination Type |
DBCO-nnAA-sidechain PEG12-PNU
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