Linker Information
General Information of This Linker
| Linker ID |
LIN0TALYU
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| Linker Name |
DBCO-nAA-sidechain PEG12
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C61H92N4O18
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| Isosmiles |
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(NC[C@H](NC(C(CC1)CCC21CCN(C(CCCCC(N3C4=C(C#CC5=C(C=CC=C5)C3)C=CC=C4)=O)=O)CC2)=O)C(O)=O)=O
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| InChI |
InChI=1S/C61H92N4O18/c1-72-26-27-74-30-31-76-34-35-78-38-39-80-42-43-82-46-47-83-45-44-81-41-40-79-37-36-77-33-32-75-29-28-73-25-18-56(66)62-48-54(60(70)71)63-59(69)52-16-19-61(20-17-52)21-23-64(24-22-61)57(67)12-6-7-13-58(68)65-49-53-10-3-2-8-50(53)14-15-51-9-4-5-11-55(51)65/h2-5,8-11,52,54H,6-7,12-13,16-49H2,1H3,(H,62,66)(H,63,69)(H,70,71)/t54-/m0/s1
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| InChIKey |
VKRBODGGBVRCSY-XSMLMOGHSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1169.417
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Polar area
|
246.88
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Complexity
|
2125.558438
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xlogp Value
|
4.1971
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Heavy Count
|
83
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Rot Bonds
|
46
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Hbond acc
|
17
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker