Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0XJCNE
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| ADC Name |
AMT-253
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| Synonyms |
AMT-253; AMT 253; AMT253
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| Organization |
Multitude Therapeutics, Inc.
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| Drug Status |
Phase 1/2
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| Indication |
In total 2 Indication(s)
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| Drug-to-Antibody Ratio |
8
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| Antibody Name |
A humanized MUC18-targeting IgG1 antibody
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Antibody Info | ||||
| Antigen Name |
Cell surface glycoprotein MUC18 (MCAM)
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Antigen Info | ||||
| Payload Name |
Exatecan
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
T1000
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Linker Info | ||||
| Conjugate Type |
Undisclosed
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