Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0VYGBA
|
|||||
|---|---|---|---|---|---|---|
| ADC Name |
Araris ADC
|
|||||
| Synonyms |
Anti-Nectin-4 ADC(Araris Biotech); ArarisADC; Araris-ADC
Click to Show/Hide
|
|||||
| Organization |
Araris Biotech AG
|
|||||
| Drug Status |
Investigative
|
|||||
| Indication |
In total 1 Indication(s)
|
|||||
| Drug-to-Antibody Ratio |
2
|
|||||
| Antibody Name |
Enfortumab
|
Antibody Info | ||||
| Antigen Name |
Nectin-4 (NECTIN4)
|
Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
|
Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
|
Target Info | ||||
| Linker Name |
Cathepsin B cleavable linker
|
|||||
| Conjugate Type |
Site-specific enzymatic conjugation approach
|
|||||
