Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0VYGBA
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| ADC Name |
Araris ADC
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| Synonyms |
Anti-Nectin-4 ADC(Araris Biotech); ArarisADC; Araris-ADC
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| Organization |
Araris Biotech AG
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| Drug Status |
Clinical candidate
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| Indication |
In total 1 Indication(s)
Breast cancer [ICD11:2C60-2C65]
Clinical candidate
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| Drug-to-Antibody Ratio |
2
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| Antibody Name |
Enfortumab
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Antibody Info | ||||
| Antigen Name |
Nectin-4 (NECTIN4)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Cathepsin B cleavable linker
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| Conjugate Type |
Site-specific enzymatic conjugation approach
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