General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0VXFLL
ADC Name
FGFR2/FGFR4 dual targeting antibody-drug conjugate
Synonyms
FGFR2/FGFR4 dual targeting antibody-drug conjugate (Novartis/MorphoSys)
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Organization
Novartis Institutes for Biomedical Research, Inc.; Novartis AG; MorphoSys AG
Drug Status
Terminated
Indication
In total 3 Indication(s)
Breast cancer
Investigative
.
Gastric cancer
Investigative
.
Lung cancer
Investigative
.
Structure
Antibody Name
Undisclosed
Antigen Name
Fibroblast growth factor receptor 2 (FGFR2); Fibroblast growth factor receptor 4 (FGFR4)
 Antigen Info 
Payload Name
Mertansine DM1
 Payload Info 
Therapeutic Target
Microtubule (MT)
 Target Info 
Linker Name
Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)
 Linker Info