Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0UXBCL
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| ADC Name |
37828728 ADC 2
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| Synonyms |
ADC 2
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| Organization |
Planegg-Martinsried.; Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP).; Humboldt Universität zu Berlin.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
5.51
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| Structure |
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| Antibody Name |
Trastuzumab
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
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Antigen Info | ||||
| Payload Name |
Exatecan
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
P5 (PEG2)-VC-PAB
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
P5 (PEG2)-VC-PAB-exatecan
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