Linker Information
General Information of This Linker
| Linker ID |
LIN0XQQDZ
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| Linker Name |
P5 (PEG2)-VC-PAB
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C31H43N6O9P
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| Isosmiles |
CC([C@H](NC(C1=CC=C(NP(C#C)(OCCOCCO)=O)C=C1)=O)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(CO)C=C2)=O)=O)C
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| InChI |
InChI=1S/C31H43N6O9P/c1-4-47(44,46-19-18-45-17-16-38)37-25-13-9-23(10-14-25)28(40)36-27(21(2)3)30(42)35-26(6-5-15-33-31(32)43)29(41)34-24-11-7-22(20-39)8-12-24/h1,7-14,21,26-27,38-39H,5-6,15-20H2,2-3H3,(H,34,41)(H,35,42)(H,36,40)(H,37,44)(H3,32,33,43)/t26-,27-,47?/m0/s1
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| InChIKey |
AQQRNCMOTFHDHU-YFSOAOLFSA-N
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| Pharmaceutical Properties |
Molecule Weight
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674.692
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Polar area
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230.44
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Complexity
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1350.611831
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xlogp Value
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1.7265
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Heavy Count
|
47
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Rot Bonds
|
20
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Hbond acc
|
9
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Hbond Donor
|
8
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Each Antibody-drug Conjugate Related to This Linker