Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0URDDC
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| ADC Name |
RS7-DL 13
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| Synonyms |
RS7-DL 13
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| Organization |
Shanghai Institute of Materia Medica.;University of Chinese Academy of Sciences.; Shanghai Mabstone Biotechnologies, Ltd.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
8
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| Structure |
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| Antibody Name |
hRS7
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Antibody Info | ||||
| Antigen Name |
Tumor-associated calcium signal transducer 2 (TACSTD2)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Payload Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Mal-PEG4-Lys (PEG24)-Cit-PAB
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Linker Info | ||||
| Conjugate Type |
Site-specific conjugation at Heavy chain K274C, V422C via THIOMABs.
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| Combination Type |
DL 13
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