General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0TSGYV
ADC Name
muFR1-22-sulfo-SPDB-DM4
Synonyms
muFR1 22 sulfo SPDB DM4
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Organization
ImmunoGen, Inc.
Drug Status
Investigative
Indication
In total 2 Indication(s)
Cervical cancer
Investigative
.
Ovarian cancer
Investigative
.
Drug-to-Antibody Ratio
3.5-4
Structure
Antibody Name
mu-FR1-22
 Antibody Info 
Antigen Name
Folate receptor alpha (FOLR1)
 Antigen Info 
Payload Name
Mertansine DM4
 Payload Info 
Therapeutic Target
Microtubule (MT)
 Target Info 
Linker Name
Sulfo-SPDB
 Linker Info 
Conjugate Type
Random conjugation through nucleophilic lysines.
Combination Type
Soravtansine