Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0SOAPH
|
|||||
|---|---|---|---|---|---|---|
| ADC Name |
H01L02-DM4
|
|||||
| Synonyms |
H01L02 DM4
Click to Show/Hide
|
|||||
| Organization |
Daiichi Sankyo Co., Ltd.;
|
|||||
| Drug Status |
Investigative
|
|||||
| Indication |
In total 2 Indication(s)
Ovarian cancer [ICD11:2C73]
Investigative
Renal cell carcinoma [ICD11:2C90]
Investigative
|
|||||
| Drug-to-Antibody Ratio |
3.6
|
|||||
| Antibody Name |
Anti-CDH6 mAb H01L02
|
Antibody Info | ||||
| Antigen Name |
Cadherin-6 (CDH6)
|
Antigen Info | ||||
| Payload Name |
Mertansine DM4
|
Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
|
Target Info | ||||
| Linker Name |
Sulfo-SPDB
|
Linker Info | ||||
| Conjugate Type |
Random conjugation through nucleophilic lysines.
|
|||||
| Combination Type |
Soravtansine
|
|||||
If you find any error in data or bug in web service, please kindly report it to Dr. Shen et al.