Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0SDFHH
|
|||||
|---|---|---|---|---|---|---|
| ADC Name |
cN114306633A C-3
|
|||||
| Synonyms |
C-3
Click to Show/Hide
|
|||||
| Organization |
MABWELL (SHANGHAI) BIOSCIENCE CO., LTD. | JIANGSU MABWELL HEALTH PHARMACEUTICAL R&D CO., LTD.
|
|||||
| Drug Status |
Investigative
|
|||||
| Drug-to-Antibody Ratio |
4
|
|||||
| Structure |
|
|||||
| Antibody Name |
pertuzumab
|
Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
|
Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
|
Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
|
Target Info | ||||
| Linker Name |
CN114306633A-C-3-linker
|
Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
|
|||||
| Combination Type |
CN114306633A-C-3-linker-MMAE
|
|||||