Linker Information
General Information of This Linker
| Linker ID |
LIN0ABZPP
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| Linker Name |
CN114306633A-C-3-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C60H68F4N8O17S2
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| Isosmiles |
CC([C@H](NC(COCCOCCOCCOC1=CC(C(F)(F)F)=C(N2C(C(SC3=CC=C(C=C3)C(N4CCOCC4)=O)=C(SC5=CC=C(C(N6CCOCC6)=O)C=C5)C2=O)=O)C=C1F)=O)C(N[C@@H](CCCNC(N)=O)C(NC7=CC=C(C=C7)COC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C60H68F4N8O17S2/c1-36(2)49(53(75)68-45(4-3-17-66-58(65)80)52(74)67-40-11-5-37(6-12-40)34-89-59(81)82)69-48(73)35-87-29-28-85-26-27-86-30-31-88-47-32-43(60(62,63)64)46(33-44(47)61)72-56(78)50(90-41-13-7-38(8-14-41)54(76)70-18-22-83-23-19-70)51(57(72)79)91-42-15-9-39(10-16-42)55(77)71-20-24-84-25-21-71/h5-16,32-33,36,45,49H,3-4,17-31,34-35H2,1-2H3,(H,67,74)(H,68,75)(H,69,73)(H,81,82)(H3,65,66,80)/t45-,49-/m0/s1
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| InChIKey |
PBANXELPCGVIKP-MAVZNXLXSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1313.369
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Polar area
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322.33
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Complexity
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3028.598608
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xlogp Value
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5.7947
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Heavy Count
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91
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Rot Bonds
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31
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Hbond acc
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18
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Hbond Donor
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6
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Each Antibody-drug Conjugate Related to This Linker