Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0RRFSP
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| ADC Name |
Blinatumomab-Compound 31
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| Synonyms |
Blinatumomab Compound 31
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| Organization |
Rongchang Pharmaceuticals Ltd.
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Acute lymphoblastic leukemia [ICD11:2B33]
Investigative
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| Drug-to-Antibody Ratio |
3.5-4
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| Antibody Name |
Blinatumomab
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Antibody Info | ||||
| Antigen Name |
B-lymphocyte antigen CD19 (CD19); T-cell surface glycoprotein CD3 delta chain (CD3D)
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Antigen Info | ||||
| Payload Name |
Auristatin 0101
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Blinatumomab-Compound 31 linker
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| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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