Antibody Information
General Information of This Antibody
Antibody ID | ANI0DYEJC |
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Antibody Name | Blinatumomab |
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Brand Name | BLINCYTO |
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Organization | Amgen, Inc.; BeiGene Ltd.; MedImmune LLC |
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Indication | B cell acute lymphoblastic leukemia; Burkitt's lymphoma; B-cell acute lymphoblastic leukemia |
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Approval Date | Dec. 2014 |
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Synonyms |
MEDI-538; MT-103; AMG103; BITE MT-103; bscCD19xCD3; MEDI-538; MT103
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Antibody Type | Bispecific antibody (BsAb) |
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Antibody Subtype | Murine IgG |
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Antigen Name | B-lymphocyte antigen CD19 (CD19); T-cell surface glycoprotein CD3 delta chain (CD3;TPBG) |
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Heavy Chain Sequence |
DIQLTQSPASLAVSLGQRATISCKASQSVDYDGDSYLNWYQQIPGQPPKLLIYDASNLVS
GIPPRFSGSGSGTDFTLNIHPVEKVDAATYHCQQSTEDPWTFGGGTKLEIKGGGGSGGGG SGGGGSQVQLQQSGAELVRPGSSVKISCKASGYAFSSYWMNWVKQRPGQGLEWIGQIWPG DGDTNYNGKFKGKATLTADESSSTAYMQLSSLASEDSAVYFCARRETTTVGRYYYAMDYW GQGTTVTVSSGGGGSDIKLQQSGAELARPGASVKMSCKTSGYTFTRYTMHWVKQRPGQGL EWIGYINPSRGYTNYNQKFKDKATLTTDKSSSTAYMQLSSLTSEDSAVYYCARYYDDHYC LDYWGQGTTLTVSSVEGGSGGSGGSGGSGGVDDIQLTQSPAIMSASPGEKVTMTCRASSS VSYMNWYQQKSGTSPKRWIYDTSKVASGVPYRFSGSGSGTSYSLTISSMEAEDAATYYCQ QWSSNPLTFGAGTKLELKHHHHHH Click to Show/Hide
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Each Antibody-drug Conjugate Related to This Antibody
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