Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0RJKWE
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| ADC Name |
STRO-001
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| Synonyms |
BN301; SP-7219; SP-7675; SP-7676; STRO 001; STRO- 001; STRO-001
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| Organization |
Sutro Biopharma, Inc.; BioNova Pharmaceuticals (Shanghai) Ltd.; Piramal Pharma Solutions, Inc.
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| Drug Status |
Phase 1/2 (Terminated)
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| Indication |
In total 4 Indication(s)
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| Drug-to-Antibody Ratio |
2
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| Structure |
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| Antibody Name |
Bezetabart
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Antibody Info | ||||
| Antigen Name |
HLA class II histocompatibility antigen gamma chain (CD74)
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Antigen Info | ||||
| Payload Name |
Maytansinoid derivative
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Cys-12 ADC linker
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Linker Info | ||||
| Conjugate Type |
Enzymatic Catalysis
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| Combination Type |
debotansine
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| Special Approval(s) |
Orphan drug(FDA)
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| Puchem SID | ||||||
| Drugbank ID | ||||||
| TTD ID | ||||||
| ChEBI ID | ||||||
