Linker Information
General Information of This Linker
| Linker ID |
LIN0ZKOQW
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| Linker Name |
Cys-12 ADC linker
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| Linker Type |
Thiol-sensitive linker
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| Antibody-Linker Relation |
Uncleavable
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| Structure |
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| Formula |
C29H36N2O6
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| Isosmiles |
CCOCCOCCOCCOCCC(=O)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc21
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| InChI |
InChI=1S/C29H36N2O6/c1-2-34-17-18-36-21-22-37-20-19-35-16-14-28(32)30-15-13-29(33)31-23-26-9-4-3-7-24(26)11-12-25-8-5-6-10-27(25)31/h3-10H,2,13-23H2,1H3,(H,30,32)
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| InChIKey |
OKHPKKDDESHHKQ-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
508.615
|
Polar area
|
86.33
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Complexity
|
508.2573369
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xlogp Value
|
2.9157
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Heavy Count
|
37
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Rot Bonds
|
16
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Hbond acc
|
6
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Hbond Donor
|
1
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Each Antibody-drug Conjugate Related to This Linker