Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0QCPHD
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| ADC Name |
ADC-AVP-04
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| Synonyms |
ADC AVP 04; ADC AVP-04; AVP04-TCO-MMAE
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| Organization |
Avipep Pty Ltd.
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| Drug Status |
Investigative
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| Indication |
In total 2 Indication(s)
Gastric cancer [ICD11:2B72]
Investigative
Ovarian cancer [ICD11:2C73]
Investigative
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| Drug-to-Antibody Ratio |
4
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| Structure |
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| Antibody Name |
AVP04
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Antibody Info | ||||
| Antigen Name |
Tumor-associated glycoprotein 72 (TAG-72)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Maleimide-functionalized TCO
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Linker Info | ||||
| Conjugate Type |
This maleimide-functionalized TCO-MMAE linker 1 was site-specifically conjugated to four engineered cysteine residues.
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| Combination Type |
TCO-MMAE
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