Linker Information
General Information of This Linker
| Linker ID |
LIN0BVBXS
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|---|---|---|---|---|---|---|
| Linker Name |
Maleimide-functionalized TCO
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| Linker Type |
Flexible dual-reactive (bioorthogonal/thiol) linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C83H153N5O35
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| Isosmiles |
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)C(CCCCNC(=O)C1(C)CC/C=C\C(O)CC1)NC(=O)CCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O
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| InChI |
InChI=1S/C83H153N5O35/c1-83(14-5-3-7-75(89)11-15-83)82(95)86-16-6-4-8-76(87-78(91)13-20-97-25-28-101-33-34-102-29-26-98-21-17-84-77(90)12-19-88-79(92)9-10-80(88)93)81(94)85-18-22-99-27-30-103-35-36-105-39-40-107-43-44-109-47-48-111-51-52-113-55-56-115-59-60-117-63-64-119-67-68-121-71-72-123-74-73-122-70-69-120-66-65-118-62-61-116-58-57-114-54-53-112-50-49-110-46-45-108-42-41-106-38-37-104-32-31-100-24-23-96-2/h3,7,9-10,75-76,89H,4-6,8,11-74H2,1-2H3,(H,84,90)(H,85,94)(H,86,95)(H,87,91)/b7-3-
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| InChIKey |
JEISEYJJRVVVTE-CLTKARDFSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1781.137
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Polar area
|
432.45
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Complexity
|
123
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xlogp Value
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0.2873
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Heavy Count
|
123
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Rot Bonds
|
98
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Hbond acc
|
35
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker
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