General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0PZBQW
ADC Name
WO2024110905A1 ADC2-10
Synonyms
WO2024110905A1 ADC2-10
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Organization
BEIGENE, LTD. | BEIGENE SWITZERLAND GMBH
Drug Status
Investigative
Drug-to-Antibody Ratio
8
Structure
Antibody Name
undisclosed
Antigen Name
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5)
 Antigen Info 
Payload Name
Exatecan
 Payload Info 
Therapeutic Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
Linker of ADC2-10
 Linker Info 
Conjugate Type
Cysteine-maleimide conjugation