Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0OLHCS
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|---|---|---|---|---|---|---|
| ADC Name |
Brentuximab-Compound 75
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| Synonyms |
Brentuximab Compound 75
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| Organization |
Rongchang Pharmaceuticals Ltd.
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Hodgkin lymphoma [ICD11:2B30]
Investigative
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| Drug-to-Antibody Ratio |
3.5-4
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| Antibody Name |
Brentuximab
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Antibody Info | ||||
| Antigen Name |
Tumor necrosis factor receptor superfamily member 8 (TNFRSF8)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Brentuximab-Compound 75 linker
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| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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