Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0NLWKV
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| ADC Name |
SGN-CD19B
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| Synonyms |
SGN CD19B; SGNCD19B
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| Organization |
Seagen Inc.
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| Drug Status |
Terminated in phase 1
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| Indication |
In total 2 Indication(s)
Diffuse large B-cell lymphoma [ICD11:2A81]
Terminated in phase 1
Follicular lymphoma [ICD11:2A80]
Terminated in phase 1
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| Drug-to-Antibody Ratio |
2
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| Structure |
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| Antibody Name |
Anti-CD19 mAb hBU12ec
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Antibody Info | ||||
| Antigen Name |
B-lymphocyte antigen CD19 (CD19)
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Antigen Info | ||||
| Payload Name |
SGD-1882
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Payload Info | ||||
| Therapeutic Target |
Human Deoxyribonucleic acid (hDNA)
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Target Info | ||||
| Linker Name |
Mc-Val-Ala
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Linker Info | ||||
| Conjugate Type |
Site-specific conjugation through the engineered cysteine (THIOMAB, Cys239).
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| Combination Type |
SGD-1910
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| TTD ID | ||||||
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