Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0MEKVD
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|---|---|---|---|---|---|---|
| ADC Name |
Anti-CD7 MMAE ADC
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| Drug Status |
Investigative
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| Indication |
In total 2 Indication(s)
Acute myeloid leukaemia [ICD11:2A60]
Investigative
Mature T-cell lymphoma [ICD11:2A90]
Investigative
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| Drug-to-Antibody Ratio |
2.6
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| Structure |
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| Antibody Name |
Human Anti-CD7 mAb IgG1
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Antibody Info | ||||
| Antigen Name |
T-cell antigen CD7 (CD7)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
|
Target Info | ||||
| Linker Name |
PermaLink-PEG4-Val-Cit-PAB
|
Linker Info | ||||
| Conjugate Type |
PermaLink bioconjugation chemistry.
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