Linker Information
General Information of This Linker
| Linker ID |
LIN0CTJFB
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
PermaLink-PEG4-Val-Cit-PAB
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C42H65N7O10
|
|||||
| Isosmiles |
C=C.C=Cc1cc(C)nc(CCC(=O)NCCOCCOCCOCCOCCC(=O)NC(C(=O)NC(CCCNC(N)=O)C(=O)Nc2ccc(CO)cc2)C(C)C)c1
|
|||||
| InChI |
InChI=1S/C40H61N7O10.C2H4/c1-5-30-25-29(4)44-33(26-30)12-13-35(49)42-16-18-55-20-22-57-24-23-56-21-19-54-17-14-36(50)47-37(28(2)3)39(52)46-34(7-6-15-43-40(41)53)38(51)45-32-10-8-31(27-48)9-11-32;1-2/h5,8-11,25-26,28,34,37,48H,1,6-7,12-24,27H2,2-4H3,(H,42,49)(H,45,51)(H,46,52)(H,47,50)(H3,41,43,53);1-2H2
|
|||||
| InChIKey |
IQSSUSSJTWTWJG-UHFFFAOYSA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
828.021
|
Polar area
|
241.56
|
||
|
Complexity
|
59
|
xlogp Value
|
2.54562
|
|||
|
Heavy Count
|
59
|
Rot Bonds
|
30
|
|||
|
Hbond acc
|
11
|
Hbond Donor
|
7
|
|||
Each Antibody-drug Conjugate Related to This Linker
If you find any error in data or bug in web service, please kindly report it to Dr. Shen et al.