Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0LPHMB
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| ADC Name |
f1-SMCC-DM1
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| Synonyms |
F1-SMCC-DM1
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| Organization |
Shanghai Hongcheng Pharmaceutical Co. Ltd.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
5.5
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| Structure |
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| Antibody Name |
F1
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Antibody Info | ||||
| Antigen Name |
Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1)
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Antigen Info | ||||
| Payload Name |
Mertansine DM1
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Succinimidyl-4- (N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)
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Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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| Combination Type |
SMCC-DM1
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