Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
ADC ID |
DRG0KJXCN
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ADC Name |
Blinatumomab-Compound 49
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Synonyms |
Blinatumomab Compound 49
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Organization |
Rongchang Pharmaceuticals Ltd.
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Drug Status |
Investigative
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Indication |
In total 1 Indication(s)
Acute lymphoblastic leukemia [ICD11:2B33]
Investigative
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Drug-to-Antibody Ratio |
1-2
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Antibody Name |
Blinatumomab
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Antibody Info | ||||
Antigen Name |
B-lymphocyte antigen CD19 (CD19); T-cell surface glycoprotein CD3 delta chain (CD3D)
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Antigen Info | ||||
Payload Name |
PBD dimer
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Payload Info | ||||
Therapeutic Target |
Human Deoxyribonucleic acid (hDNA)
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Target Info | ||||
Linker Name |
Blinatumomab-Compound 49 linker
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Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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