Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ID: DRG0ITUYO)
| ADC Name |
HK40112172A Antibody-drug conjugate (24)
|
|||||
|---|---|---|---|---|---|---|
| Synonyms |
Antibody-drug conjugate (24)
Click to Show/Hide
|
|||||
| Organization |
DAIICHI SANKYO COMPANY
|
|||||
| Drug Status |
Investigative
|
|||||
| Drug-to-Antibody Ratio |
1.7
|
|||||
| Antibody Name |
Trastuzumab
|
Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (HER2)
|
Antigen Info | ||||
| Payload Name |
LT4212552T ADC25 payload
|
Payload Info | ||||
| Payload Target |
DNA topoisomerase I (TOP1)
|
Target Info | ||||
| Linker Name |
Mc-Gly-Gly-Phe-Gly
|
Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
|
|||||