Payload Information
General Information of This Payload
| Payload ID | PAY0BCEPO |
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|---|---|---|---|---|---|---|
| Name | LT4212552T ADC25 payload |
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| Synonyms |
SCHEMBL17193754; SCHEMBL30497471
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| Target | DNA topoisomerase I (TOP1) | |||||
| Structure |
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| Formula | C30H33FN4O5 |
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| Isosmiles | CC1=C(C2=C3C=C1F)CC[C@H](NC(CCCCCN)=O)C2=C(C(C4=CC([C@@]5(O)CC)=C6COC5=O)=N3)CN4C6=O |
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| PubChem CID | ||||||
| InChI |
InChI=1S/C30H33FN4O5/c1-3-30(39)19-11-23-27-17(13-35(23)28(37)18(19)14-40-29(30)38)26-21(33-24(36)7-5-4-6-10-32)9-8-16-15(2)20(31)12-22(34-27)25(16)26/h11-12,21,39H,3-10,13-14,32H2,1-2H3,(H,33,36)/t21-,30-/m0/s1
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| InChIKey |
NJEGEXSBAKBIRG-JRPXNJEYSA-N
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| Pharmaceutical Properties | Molecule Weight |
548.615 |
Polar area |
136.54 |
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Complexity |
1601.953336 |
xlogp Value |
3.14972 |
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Heavy Count |
40 |
Rot Bonds |
7 |
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Hbond acc |
8 |
Hbond Donor |
3 |
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Each Antibody-drug Conjugate Related to This Payload