Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0HVTSX
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| ADC Name |
ICAM1-DM1 1-10
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| Synonyms |
ICAM1-DM1
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| Organization |
Boston Childrens Hospital
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
1-10
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| Structure |
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| Antibody Name |
undisclosed
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| Antigen Name |
Intercellular adhesion molecule 1 (ICAM1)
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Antigen Info | ||||
| Payload Name |
Mertansine DM1
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Succinimidyl-4- (N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)
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Linker Info | ||||
| Conjugate Type |
Random conjugation through nucleophilic lysines
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| Combination Type |
SMCC-DM1
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