General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0HVNZU
ADC Name
SHR-4394
Synonyms
SHR-4394
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Organization
Jiangsu Hengrui Pharmaceuticals (Originator)
Drug Status
Phase 1/2
Antibody Name
Anti-PSMA mAb
 Antibody Info 
Antigen Name
Glutamate carboxypeptidase 2 (FOLH1)
 Antigen Info 
Payload Name
SHR9265
 Payload Info 
Therapeutic Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Undisclosed
The indication landscape of This ADC(2027 Update)
The clinical trial pipeline of This ADC(2027 Update)
Indication Phase 1 Phase 1/2 Phase 2 Phase 2/3 Phase 3 New Drug Application Approved
Prostate cancer
1 Trials
Trial ID
NCT06783829; CTR20250145; ChiCTR2500096042