Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0HMQNF
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| ADC Name |
Gemtuzumab-Compound 77
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| Synonyms |
Gemtuzumab Compound 77
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| Organization |
Rongchang Pharmaceuticals Ltd.
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Acute myelogenous leukemia [ICD11:2B33]
Investigative
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| Drug-to-Antibody Ratio |
3-3.5
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| Antibody Name |
Gemtuzumab
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Antibody Info | ||||
| Antigen Name |
Myeloid cell surface antigen CD33 (CD33)
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Antigen Info | ||||
| Payload Name |
Mertansine DM1
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Gemtuzumab-Compound 77 linker
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| Conjugate Type |
Random conjugation through reduced inter-chain cysteines.
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