General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0HCEEF
ADC Name
DHES-0815A
Synonyms
DHES 0815A; DHES-0815A; DHES0 815A, RG614 8; DHES0815A; RG 6148; RG-6148; RG6148
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Organization
Genentech, Inc.; Roche Holding AG
Drug Status
Phase 1 (Terminated)
Indication
In total 1 Indication(s)
Breast cancer
Phase 1
Clinical Trial
Drug-to-Antibody Ratio
2
Antibody Name
MHES0488A
 Antibody Info 
Antigen Name
Receptor tyrosine-protein kinase erbB-2 (HER2)
 Antigen Info 
Payload Name
Pyrrolo[2,1-c][1,4]benzodiazepine monoamide (PBD-MA)
 Payload Info 
Therapeutic Target
Human Deoxyribonucleic acid (hDNA)
 Target Info 
Conjugate Type
Reactive Cysteines