Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0HBMPH
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| ADC Name |
ZW-251
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| Synonyms |
ZW251; ZW 251
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| Organization |
Zymeworks BC, Inc.
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Hepatocellular carcinoma [ICD11:2C12]
Investigative
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| Structure |
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| Antibody Name |
Humanized Anti-GPC3 IgG1 mAb
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Antibody Info | ||||
| Antigen Name |
Glypican-3 (GPC3)
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Antigen Info | ||||
| Payload Name |
ZD06519
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Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
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Target Info | ||||
| Linker Name |
Mc-Gly-Gly-Phe-Gly-AM
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Linker Info | ||||
| Conjugate Type |
Endogenous interchain cysteines.
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| Combination Type |
MC-GGFG-AM-ZD06519
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